NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)
1_MNQRR 6_ SESRP 11_ GNHRL 16_ QAYAE 21_ PGKGD 26_ SGGAG 31_ PLSGS 36_ ARRGR 41_ GGGGA 46_ IRVRR 51_ PCWSG 56_ GAGRG 61_ GGPAW 66_ AVRLP 71_ TVTAG 76_ WTWPA 81_ LRTLS 86_ SLRAG 91_ PSEPH 96_ SPGRR 101_ PPRAG 106_ RPLCQ 111_ ADPQP 116_ GKAAR 121_ RSLEP 126_ DPAQT 131_ GPRPA 136_ RAAGM 141_ SEARK 146_ GPDEA 151_ EESQY 156_ DSGIE 161_ SLRSL 166_ RSLPE 171_ STSAP 176_ ASGPS 181_ DGSPQ 186_ PCTHP 191_ PGPVK 196_ EPQEK 201_ EDADG 206_ ERADS 211_ TYGSS 216_ SLTYT 221_ LSLLG 226_ GPEAE 231_ DPAPR 236_ LPLPH 241_ VGALS 246_ PQQLE 251_ ALTYI 256_ SEDGD 261_ TLVHL 266_ AVIHE 271_ APAVL 276_ LCCLA 281_ LLPQE 286_ VLDIQ 291_ NNLYQ 296_ TALHL 301_ AVHLD 306_ QPGAV 311_ RALVL 316_ KGASR 321_ ALQDR 326_ HGDTA 331_ LHVAC 336_ QRQHL 341_ ACARC 346_ LLEGR 351_ PEPGR 356_ GTSHS 361_ LDLQL 366_ QNWQG 371_ LACLH 376_ IATLQ 381_ KNQPL 386_ MELLL 391_ RNGAD 396_ IDVQE 401_ GTSGK 406_ TALHL 411_ AVETQ 416_ ERGLV 421_ QFLLQ 426_ AGAQV 431_ DARML 436_ NGCTP 441_ LHLAA 446_ GRGLM 451_ GISST 456_ LCKAG 461_ ADSLL 466_ RNVED 471_ ETPQD 476_ LTEES 481_ LVLLP 486_ FDDLK 491_ISGKL
1: Sequesters NF-kappa-B transcription factor complexes in the cytoplasm, thereby inhibiting their activity (PubMed:9315679). Sequestered complexes include NFKB1-RELA (p50-p65) and NFKB1-REL (p50-c-Rel) complexes (PubMed:9135156, PubMed:9315679). Limits B-cell activation in response to pathogens, and also plays an important role in B-cell development (By similarity)