Forkhead box protein E1 (Forkhead box protein E2) (Forkhead-related protein FKHL15) (HFKH4) (HNF-3/fork head-like protein 5) (HFKL5) (Thyroid transcription factor 2) (TTF-2)
1_MTAES 6_ GPPPP 11_ QPEVL 16_ ATVKE 21_ ERGET 26_ AAGAG 31_ VPGEA 36_ TGRGA 41_ GGRRR 46_ KRPLQ 51_ RGKPP 56_ YSYIA 61_ LIAMA 66_ IAHAP 71_ ERRLT 76_ LGGIY 81_ KFITE 86_ RFPFY 91_ RDNPK 96_ KWQNS 101_ IRHNL 106_ TLNDC 111_ FLKIP 116_ REAGR 121_ PGKGN 126_ YWALD 131_ PNAED 136_ MFESG 141_ SFLRR 146_ RKRFK 151_ RSDLS 156_ TYPAY 161_ MHDAA 166_ AAAAA 171_ AAAAA 176_ AAAAI 181_ FPGAV 186_ PAARP 191_ PYPGA 196_ VYAGY 201_ APPSL 206_ AAPPP 211_ VYYPA 216_ ASPGP 221_ CRVFG 226_ LVPER 231_ PLSPE 236_ LGPAP 241_ SGPGG 246_ SCAFA 251_ SAGAP 256_ ATTTG 261_ YQPAG 266_ CTGAR 271_ PANPS 276_ AYAAA 281_ YAGPD 286_ GAYPQ 291_ GAGSA 296_ IFAAA 301_ GRLAG 306_ PASPP 311_ AGGSS 316_ GGVET 321_ TVDFY 326_ GRTSP 331_ GQFGA 336_ LGACY 341_ NPGGQ 346_ LGGAS 351_ AGAYH 356_ ARHAA 361_ AYPGG 366_IDRFV
1: Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression