GDNF family receptor alpha-2 (GDNF receptor alpha-2) (GDNFR-alpha-2) (GFR-alpha-2) (GDNF receptor beta) (GDNFR-beta) (Neurturin receptor alpha) (NRTNR-alpha) (NTNR-alpha) (RET ligand 2) (TGF-beta-related neurotrophic factor receptor 2)
1_MILAN 6_ VFCLF 11_ FFLDE 16_ TLRSL 21_ ASPSS 26_ LQGPE 31_ LHGWR 36_ PPVDC 41_ VRANE 46_ LCAAE 51_ SNCSS 56_ RYRTL 61_ RQCLA 66_ GRDRN 71_ TMLAN 76_ KECQA 81_ ALEVL 86_ QESPL 91_ YDCRC 96_ KRGMK 101_ KELQC 106_ LQIYW 111_ SIHLG 116_ LTEGE 121_ EFYEA 126_ SPYEP 131_ VTSRL 136_ SDIFR 141_ LASIF 146_ SGTGA 151_ DPVVS 156_ AKSNH 161_ CLDAA 166_ KACNL 171_ NDNCK 176_ KLRSS 181_ YISIC 186_ NREIS 191_ PTERC 196_ NRRKC 201_ HKALR 206_ QFFDR 211_ VPSEY 216_ TYRML 221_ FCSCQ 226_ DQACA 231_ ERRRQ 236_ TILPS 241_ CSYED 246_ KEKPN 251_ CLDLR 256_ GVCRT 261_ DHLCR 266_ SRLAD 271_ FHANC 276_ RASYQ 281_ TVTSC 286_ PADNY 291_ QACLG 296_ SYAGM 301_ IGFDM 306_ TPNYV 311_ DSSPT 316_ GIVVS 321_ PWCSC 326_ RGSGN 331_ MEEEC 336_ EKFLR 341_ DFTEN 346_ PCLRN 351_ AIQAF 356_ GNGTD 361_ VNVSP 366_ KGPSF 371_ QATQA 376_ PRVEK 381_ TPSLP 386_ DDLSD 391_ STSLG 396_ TSVIT 401_ TCTSV 406_ QEQGL 411_ KANNS 416_ KELSM 421_ CFTEL 426_ TTNII 431_ PGSNK 436_ VIKPN 441_ SGPSR 446_ ARPSA 451_ ALTVL 456_SVLML
1: Receptor for neurturin (NRTN), a growth factor that supports the survival of sympathetic neurons (PubMed:10829012, PubMed:29414779, PubMed:31535977, PubMed:9182803). NRTN-binding leads to autophosphorylation and activation of the RET receptor (PubMed:31535977). Also able to mediate GDNF signaling through the RET tyrosine kinase receptor (PubMed:9182803)
2: Participates in NRTN-induced 'Ser-727' phosphorylation of STAT3