Gene name: LST1

Uniprot entry:

O00453

Protein names:

Leukocyte-specific transcript 1 protein (Protein B144)

Protein sequence:

1_MLSRN 6_ DDICI 11_ YGGLG 16_ LGGLL 21_ LLAVV 26_ LLSAC 31_ LCWLH 36_ RRVKR 41_ LERSW 46_ AQGSS 51_ EQELH 56_ YASLQ 61_ RLPVP 66_ SSEGP 71_ DLRGR 76_ DKRGT 81_ KEDPR 86_ ADYAC 91_IAENK

Protein annotations

Protein functions:

1: Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation