TNF receptor-associated factor 5 (RING finger protein 84)
1_MAYSE 6_ EHKGM 11_ PCGFI 16_ RQNSG 21_ NSISL 26_ DFEPS 31_ IEYQF 36_ VERLE 41_ ERYKC 46_ AFCHS 51_ VLHNP 56_ HQTGC 61_ GHRFC 66_ QHCIL 71_ SLREL 76_ NTVPI 81_ CPVDK 86_ EVIKS 91_ QEVFK 96_ DNCCK 101_ REVLN 106_ LYVYC 111_ SNAPG 116_ CNAKV 121_ ILGRY 126_ QDHLQ 131_ QCLFQ 136_ PVQCS 141_ NEKCR 146_ EPVLR 151_ KDLKE 156_ HLSAS 161_ CQFRK 166_ EKCLY 171_ CKKDV 176_ VVINL 181_ QNHEE 186_ NLCPE 191_ YPVFC 196_ PNNCA 201_ KIILK 206_ TEVDE 211_ HLAVC 216_ PEAEQ 221_ DCPFK 226_ HYGCA 231_ VTDKR 236_ RNLQQ 241_ HEHSA 246_ LREHM 251_ RLVLE 256_ KNVQL 261_ EEQIS 266_ DLHKS 271_ LEQKE 276_ SKIQQ 281_ LAETI 286_ KKLEK 291_ EFKQF 296_ AQLFG 301_ KNGSF 306_ LPNIQ 311_ VFASH 316_ IDKSA 321_ WLEAQ 326_ VHQLL 331_ QMVNQ 336_ QQNKF 341_ DLRPL 346_ MEAVD 351_ TVKQK 356_ ITLLE 361_ NNDQR 366_ LAVLE 371_ EETNK 376_ HDTHI 381_ NIHKA 386_ QLSKN 391_ EERFK 396_ LLEGT 401_ CYNGK 406_ LIWKV 411_ TDYKM 416_ KKREA 421_ VDGHT 426_ VSIFS 431_ QSFYT 436_ SRCGY 441_ RLCAR 446_ AYLNG 451_ DGSGR 456_ GSHLS 461_ LYFVV 466_ MRGEF 471_ DSLLQ 476_ WPFRQ 481_ RVTLM 486_ LLDQS 491_ GKKNI 496_ METFK 501_ PDPNS 506_ SSFKR 511_ PDGEM 516_ NIASG 521_ CPRFV 526_ AHSVL 531_ ENAKN 536_ AYIKD 541_ DTLFL 546_ KVAVD 551_LTDLE
1: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR