U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10)
1_MAPQV 6_ WRRRT 11_ LERCL 16_ TEVGK 21_ ATGRP 26_ ECFLT 31_ IQEGL 36_ ASKFT 41_ SLTKV 46_ LYDFN 51_ KILEN 56_ GRIHG 61_ SPLQK 66_ LVIEN 71_ FDDEQ 76_ IWQQL 81_ ELQNE 86_ PILQY 91_ FQNAV 96_ SETIN 101_ DEDIS 106_ LLPES 111_ EEQER 116_ EEDGS 121_ EIEAD 126_ DKEDL 131_ EDLEE 136_ EEVSD 141_ MGNDD 146_ PEMGE 151_ RAENS 156_ SKSDL 161_ RKSPV 166_ FSDED 171_ SDLDF 176_ DISKL 181_ EQQSK 186_ VQNKG 191_ QGKPR 196_ EKSIV 201_ DDKFF 206_ KLSEM 211_ EAYLE 216_ NIEKE 221_ EERKD 226_ DNDEE 231_ EEDID 236_ FFEDI 241_ DSDED 246_ EGGLF 251_ GSKKL 256_ KSGKS 261_ SRNLK 266_ YKDFF 271_ DPVES 276_ DEDIT 281_ NVHDD 286_ ELDSN 291_ KEDDE 296_ IAEEE 301_ AEELS 306_ ISETD 311_ EDDDL 316_ QENED 321_ NKQHK 326_ ESLKR 331_ VTFAL 336_ PDDAE 341_ TEDTG 346_ VLNVK 351_ KNSDE 356_ VKSSF 361_ EKRQE 366_ KMNEK 371_ IASLE 376_ KELLE 381_ KKPWQ 386_ LQGEV 391_ TAQKR 396_ PENSL 401_ LEETL 406_ HFDHA 411_ VRMAP 416_ VITEE 421_ TTLQL 426_ EDIIK 431_ QRIRD 436_ QAWDD 441_ VVRKE 446_ KPKED 451_ AYEYK 456_ KRLTL 461_ DHEKS 466_ KLSLA 471_ EIYEQ 476_ EYIKL 481_ NQQKT 486_ AEEEN 491_ PEHVE 496_ IQKMM 501_ DSLFL 506_ KLDAL 511_ SNFHF 516_ IPKPP 521_ VPEIK 526_ VVSNL 531_ PAITM 536_ EEVAP 541_ VSVSD 546_ AALLA 551_ PEEIK 556_ EKNKA 561_ GDIKT 566_ AAEKT 571_ ATDKK 576_ RERRK 581_ KKYQK 586_ RMKIK 591_ EKEKR 596_ RKLLE 601_ KSSVD 606_ QAGKY 611_ SKTVA 616_ SEKLK 621_ QLTKT 626_ GKASF 631_ IKDEG 636_ KDKAL 641_ KSSQA 646_ FFSKL 651_ QDQVK 656_ MQIND 661_ AKKTE 666_ KKKKK 671_ RQDIS 676_VHKLK
1: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (PubMed:12655004). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)