F-BAR domain only protein 1
1_MSYFG 6_ EHFWG 11_ EKNHG 16_ FEVLY 21_ HSVKQ 26_ GPIST 31_ KELAD 36_ FIRER 41_ ATIEE 46_ TYSKA 51_ MAKLS 56_ KLASN 61_ GTPMG 66_ TFAPL 71_ WEVFR 76_ VSSDK 81_ LALCH 86_ LELTR 91_ KLQDL 96_ IKDVL 101_ RYGEE 106_ QLKTH 111_ KKCKE 116_ EVVST 121_ LDAVQ 126_ VLSGV 131_ SQLLP 136_ KSREN 141_ YLNRC 146_ MDQER 151_ LRRES 156_ TSQKE 161_ MDKAE 166_ TKTKK 171_ AAESL 176_ RRSVE 181_ KYNSA 186_ RADFE 191_ QKMLD 196_ SALRF 201_ QAMEE 206_ THLRH 211_ MKALL 216_ GSYAH 221_ SVEDT 226_ HVQIG 231_ QVHEE 236_ FKQNI 241_ ENVSV 246_ EMLLR 251_ KFAES 256_ KGTGR 261_ EKPGP 266_ LDFEA 271_ YSAAA 276_ LQEAM 281_ KRLRG 286_ AKAFR 291_ LPGLS 296_ RRERE 301_ PEPPA 306_ AVDFL 311_ EPDSG 316_ TCPEV 321_ DEEGF 326_ TVRPD 331_ VTQNS 336_ TAEPS 341_ RFSSS 346_ DSDFD 351_ DEEPR 356_ KFYVH 361_ IKPAP 366_ ARAPA 371_ CSPEA 376_ AAAQL 381_ RATAG 386_ SLILP 391_ PGPGG 396_ TMKRH 401_ SSRDA 406_ AGKPQ 411_ RPRSA 416_ PRTSS 421_ CAERL 426_ QSEEQ 431_ VSKNL 436_ FGPPL 441_ ESAFD 446_ HEDFT 451_ GSSSL 456_ GFTSS 461_ PSPFS 466_ SSSPE 471_ NVEDS 476_ GLDSP 481_ SHAAP 486_ GPSPD 491_ SWVPR 496_ PGTPQ 501_ SPPSC 506_ RAPPP 511_ EARGI 516_ RAPPL 521_ PDSPQ 526_ PLASS 531_ PGPWG 536_ LEALA 541_ GGDLM 546_ PAPAD 551_ PTARE 556_ GLAAP 561_ PRRLR 566_ SRKVS 571_ CPLTR 576_ SNGDL 581_ SRSLS 586_ PSPLG 591_ SSAAS 596_ TALER 601_ PSFLS 606_ QTGHG 611_ VSRGP 616_ SPVVL 621_ GSQDA 626_ LPIAT 631_ AFTEY 636_ VHAYF 641_ RGHSP 646_ SCLAR 651_ VTGEL 656_ TMTFP 661_ AGIVR 666_ VFSGT 671_ PPPPV 676_ LSFRL 681_ VHTTA 686_ IEHFQ 691_ PNADL 696_ LFSDP 701_ SQSDP 706_ ETKDF 711_ WLNMA 716_ ALTEA 721_ LQRQA 726_ EQNPT 731_ ASYYN 736_ VVLLR 741_ YQFSR 746_ PGPQS 751_ VPLQL 756_ SAHWQ 761_ CGATL 766_ TQVSV 771_ EYGYR 776_ PGATA 781_ VPTPL 786_ TNVQI 791_ LLPVG 796_ EPVTN 801_ VRLQP 806_ AATWN 811_ LEEKR 816_ LTWRL 821_ PDVSE 826_ AGGSG 831_ RLSAS 836_ WEPLS 841_ GPSTP 846_ SPVAA 851_ QFTSE 856_ GTTLS 861_ GVDLE 866_ LVGSG 871_ YRMSL 876_ VKRRF 881_ATGMY
1: Functions in an early step of clathrin-mediated endocytosis (PubMed:30822429). Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. May regulate Bmp signaling by regulating clathrin-mediated endocytosis of Bmp receptors. Involved in the regulation of T-cell poliferation and activation (PubMed:30822429, PubMed:32098969). Affects TCR clustering upon receptor triggering and modulates its internalisation, playing a role in TCR-dependent T-cell activation (PubMed:32098969)