Gene name: CDC42EP2

Uniprot entry:

O14613

Protein names:

Cdc42 effector protein 2 (Binder of Rho GTPases 1)

Protein sequence:

1_MSTKV 6_ PIYLK 11_ RGSRK 16_ GKKEK 21_ LRDLL 26_ SSDMI 31_ SPPLG 36_ DFRHT 41_ IHIGS 46_ GGGSD 51_ MFGDI 56_ SFLQG 61_ KFHLL 66_ PGTMV 71_ EGPEE 76_ DGTFD 81_ LPFQF 86_ TRTAT 91_ VCGRE 96_ LPDGP 101_ SPLLK 106_ NAISL 111_ PVIGG 116_ PQALT 121_ LPTAQ 126_ APPKP 131_ PRLHL 136_ ETPQP 141_ SPQEG 146_ GSVDI 151_ WRIPE 156_ TGSPN 161_ SGLTP 166_ ESGAE 171_ EPFLS 176_ NASSL 181_ LSLHV 186_ DLGPS 191_ ILDDV 196_ LQIMD 201_QDLDS

Protein annotations

Protein functions:

1: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner