CDP-diacylglycerol--inositol 3-phosphatidyltransferase (EC 2.7.8.11) (Phosphatidylinositol synthase) (PI synthase) (PtdIns synthase)
1_MPDEN 6_ IFLFV 11_ PNLIG 16_ YARIV 21_ FAIIS 26_ FYFMP 31_ CCPLT 36_ ASSFY 41_ LLSGL 46_ LDAFD 51_ GHAAR 56_ ALNQG 61_ TRFGA 66_ MLDML 71_ TDRCS 76_ TMCLL 81_ VNLAL 86_ LYPGA 91_ TLFFQ 96_ ISMSL 101_ DVASH 106_ WLHLH 111_ SSVVR 116_ GSESH 121_ KMIDL 126_ SGNPV 131_ LRIYY 136_ TSRPA 141_ LFTLC 146_ AGNEL 151_ FYCLL 156_ YLFHF 161_ SEGPL 166_ VGSVG 171_ LFRMG 176_ LWVTA 181_ PIALL 186_ KSLIS 191_ VIHLI 196_ TAARN 201_ MAALD 206_AADRA
1: Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme