Protein unc-13 homolog B (Munc13-2) (munc13)
1_MSLLC 6_ VRVKR 11_ AKFQG 16_ SPDKF 21_ NTYVT 26_ LKVQN 31_ VKSTT 36_ VAVRG 41_ DQPSW 46_ EQDFM 51_ FEISR 56_ LDLGL 61_ SVEVW 66_ NKGLI 71_ WDTMV 76_ GTVWI 81_ ALKTI 86_ RQSDE 91_ EGPGE 96_ WSTLE 101_ AETLM 106_ KDDEI 111_ CGTRN 116_ PTPHK 121_ ILLDT 126_ RFELP 131_ FDIPE 136_ EEARY 141_ WTYKW 146_ EQINA 151_ LGADN 156_ EYSSQ 161_ EESQR 166_ KPLPT 171_ AAAQC 176_ SFEDP 181_ DSAVD 186_ DRDSD 191_ YRSET 196_ SNSFP 201_ PPYHT 206_ ASQPN 211_ ASVHQ 216_ FPVPV 221_ RSPQQ 226_ LLLQG 231_ SSRDS 236_ CNDSM 241_ QSYDL 246_ DYPER 251_ RAISP 256_ TSSSR 261_ YGSSC 266_ NVSQG 271_ SSQLS 276_ ELDQY 281_ HEQDD 286_ DHRET 291_ DSIHS 296_ CHSSH 301_ SLSRD 306_ GQAGF 311_ GEQEK 316_ PLEVT 321_ GQAEK 326_ EAACE 331_ PKEMK 336_ EDATT 341_ HPPPD 346_ LVLQK 351_ DHFLG 356_ PQESF 361_ PEENA 366_ SSPFT 371_ QARAH 376_ WIRAV 381_ TKVRL 386_ QLQEI 391_ PDDGD 396_ PSLPQ 401_ WLPEG 406_ PAGGL 411_ YGIDS 416_ MPDLR 421_ RKKPL 426_ PLVSD 431_ LSLVQ 436_ SRKAG 441_ ITSAM 446_ ATRTS 451_ LKDEE 456_ LKSHV 461_ YKKTL 466_ QALIY 471_ PISCT 476_ TPHNF 481_ EVWTA 486_ TTPTY 491_ CYECE 496_ GLLWG 501_ IARQG 506_ MRCSE 511_ CGVKC 516_ HEKCQ 521_ DLLNA 526_ DCLQR 531_ AAEKS 536_ CKHGA 541_ EDRTQ 546_ NIIMA 551_ MKDRM 556_ KIRER 561_ NKPEI 566_ FEVIR 571_ DVFTV 576_ NKAAH 581_ VQQMK 586_ TVKQS 591_ VLDGT 596_ SKWSA 601_ KITIT 606_ VVCAQ 611_ GLQAK 616_ DKTGS 621_ SDPYV 626_ TVQVS 631_ KTKKR 636_ TKTIF 641_ GNLNP 646_ VWEEK 651_ FHFEC 656_ HNSSD 661_ RIKVR 666_ VWDED 671_ DDIKS 676_ RVKQR 681_ LKRES 686_ DDFLG 691_ QTIIE 696_ VRTLS 701_ GEMDV 706_ WYNLE 711_ KRTDK 716_ SAVSG 721_ AIRLQ 726_ ISVEI 731_ KGEEK 736_ VAPYH 741_ VQYTC 746_ LHENL 751_ FHYLT 756_ DIQGS 761_ GGVRI 766_ PEARG 771_ DDAWK 776_ VYFDE 781_ TAQEI 786_ VDEFA 791_ MRYGI 796_ ESIYQ 801_ AMTHF 806_ ACLSS 811_ KYMCP 816_ GVPAV 821_ MSTLL 826_ ANINA 831_ YYAHT 836_ TASTN 841_ VSASD 846_ RFAAS 851_ NFGKE 856_ RFVKL 861_ LDQLH 866_ NSLRI 871_ DLSTY 876_ RNNFP 881_ AGSPE 886_ RLQDL 891_ KSTVD 896_ LLTSI 901_ TFFRM 906_ KVQEL 911_ QSPPR 916_ ASQVV 921_ KDCVK 926_ ACLNS 931_ TYEYI 936_ FNNCH 941_ DLYSR 946_ QYQLK 951_ QELPP 956_ EEQGP 961_ SIRNL 966_ DFWPK 971_ LITLI 976_ VSIIE 981_ EDKNS 986_ YTPVL 991_ NQFPQ 996_ ELNVG 1001_ KVSAE 1006_ VMWHL 1011_ FAQDM 1016_ KYALE 1021_ EHEKD 1026_ HLCKS 1031_ ADYMN 1036_ LHFKV 1041_ KWLHN 1046_ EYVRD 1051_ LPVLQ 1056_ GQVPE 1061_ YPAWF 1066_ EQFVL 1071_ QWLDE 1076_ NEDVS 1081_ LEFLR 1086_ GALER 1091_ DKKDG 1096_ FQQTS 1101_ EHALF 1106_ SCSVV 1111_ DVFTQ 1116_ LNQSF 1121_ EIIRK 1126_ LECPD 1131_ PSILA 1136_ HYMRR 1141_ FAKTI 1146_ GKVLM 1151_ QYADI 1156_ LSKDF 1161_ PAYCT 1166_ KEKLP 1171_ CILMN 1176_ NVQQL 1181_ RVQLE 1186_ KMFEA 1191_ MGGKE 1196_ LDLEA 1201_ ADSLK 1206_ ELQVK 1211_ LNTVL 1216_ DELSM 1221_ VFGNS 1226_ FQVRI 1231_ DECVR 1236_ QMADI 1241_ LGQVR 1246_ GTGNA 1251_ SPDAR 1256_ ASAAQ 1261_ DADSV 1266_ LRPLM 1271_ DFLDG 1276_ NLTLF 1281_ ATVCE 1286_ KTVLK 1291_ RVLKE 1296_ LWRVV 1301_ MNTME 1306_ RMIVL 1311_ PPLTD 1316_ QTGTQ 1321_ LIFTA 1326_ AKELS 1331_ HLSKL 1336_ KDHMV 1341_ REETR 1346_ NLTPK 1351_ QCAVL 1356_ DLALD 1361_ TIKQY 1366_ FHAGG 1371_ NGLKK 1376_ TFLEK 1381_ SPDLQ 1386_ SLRYA 1391_ LSLYT 1396_ QTTDT 1401_ LIKTF 1406_ VRSQT 1411_ TQGSG 1416_ VDDPV 1421_ GEVSI 1426_ QVDLF 1431_ THPGT 1436_ GEHKV 1441_ TVKVV 1446_ AANDL 1451_ KWQTA 1456_ GMFRP 1461_ FVEVT 1466_ MVGPH 1471_ QSDKK 1476_ RKFTT 1481_ KSKSN 1486_ NWAPK 1491_ YNETF 1496_ HFLLG 1501_ NEEGP 1506_ ESYEL 1511_ QICVK 1516_ DYCFA 1521_ REDRV 1526_ LGLAV 1531_ MPLRD 1536_ VTAKG 1541_ SCACW 1546_ CPLGR 1551_ KIHMD 1556_ ETGLT 1561_ ILRIL 1566_ SQRSN 1571_ DEVAR 1576_ EFVKL 1581_ KSESR 1586_STEEG
1: Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP) (By similarity). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity). In collaboration with UNC13A, facilitates neuronal dense core vesicles fusion as well as controls the location and efficiency of their synaptic release (By similarity)