Trace amine-associated receptor 5 (TaR-5) (Trace amine receptor 5) (hTaar5) (Putative neurotransmitter receptor)
1_MRAVF 6_ IQGAE 11_ EHPAA 16_ FCYQV 21_ NGSCP 26_ RTVHT 31_ LGIQL 36_ VIYLA 41_ CAAGM 46_ LIIVL 51_ GNVFV 56_ AFAVS 61_ YFKAL 66_ HTPTN 71_ FLLLS 76_ LALAD 81_ MFLGL 86_ LVLPL 91_ STIRS 96_ VESCW 101_ FFGDF 106_ LCRLH 111_ TYLDT 116_ LFCLT 121_ SIFHL 126_ CFISI 131_ DRHCA 136_ ICDPL 141_ LYPSK 146_ FTVRV 151_ ALRYI 156_ LAGWG 161_ VPAAY 166_ TSLFL 171_ YTDVV 176_ ETRLS 181_ QWLEE 186_ MPCVG 191_ SCQLL 196_ LNKFW 201_ GWLNF 206_ PLFFV 211_ PCLIM 216_ ISLYV 221_ KIFVV 226_ ATRQA 231_ QQITT 236_ LSKSL 241_ AGAAK 246_ HERKA 251_ AKTLG 256_ IAVGI 261_ YLLCW 266_ LPFTI 271_ DTMVD 276_ SLLHF 281_ ITPPL 286_ VFDIF 291_ IWFAY 296_ FNSAC 301_ NPIIY 306_ VFSYQ 311_ WFRKA 316_ LKLTL 321_ SQKVF 326_ SPQTR 331_TVDLY
1: Olfactory receptor specific for trimethylamine, a trace amine (PubMed:23393561). Also activated at lower level by dimethylethylamine (PubMed:23393561). Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food (PubMed:23393561). Trimethylamine-binding causes a conformation change that triggers signaling via G(s)-class of G alpha proteins (GNAL or GNAS) (PubMed:23393561)