Protein Wnt-9a (Protein Wnt-14)
1_MLDGS 6_ PLARW 11_ LAAAF 16_ GLTLL 21_ LAALR 26_ PSAAY 31_ FGLTG 36_ SEPLT 41_ ILPLT 46_ LEPEA 51_ AAQAH 56_ YKACD 61_ RLKLE 66_ RKQRR 71_ MCRRD 76_ PGVAE 81_ TLVEA 86_ VSMSA 91_ LECQF 96_ QFRFE 101_ RWNCT 106_ LEGRY 111_ RASLL 116_ KRGFK 121_ ETAFL 126_ YAISS 131_ AGLTH 136_ ALAKA 141_ CSAGR 146_ MERCT 151_ CDEAP 156_ DLENR 161_ EAWQW 166_ GGCGD 171_ NLKYS 176_ SKFVK 181_ EFLGR 186_ RSSKD 191_ LRARV 196_ DFHNN 201_ LVGVK 206_ VIKAG 211_ VETTC 216_ KCHGV 221_ SGSCT 226_ VRTCW 231_ RQLAP 236_ FHEVG 241_ KHLKH 246_ KYETA 251_ LKVGS 256_ TTNEA 261_ AGEAG 266_ AISPP 271_ RGRAS 276_ GAGGS 281_ DPLPR 286_ TPELV 291_ HLDDS 296_ PSFCL 301_ AGRFS 306_ PGTAG 311_ RRCHR 316_ EKNCE 321_ SICCG 326_ RGHNT 331_ QSRVV 336_ TRPCQ 341_ CQVRW 346_ CCYVE 351_ CRQCT 356_QREEV
1: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal timing of IHH expression during embryonic bone development, normal chondrocyte maturation and for normal bone mineralization during embryonic bone development. Plays a redundant role in maintaining joint integrity