Mitochondrial import inner membrane translocase subunit Tim23
1_MEGGG 6_ GSGNK 11_ TTGGL 16_ AGFFG 21_ AGGAG 26_ YSHAD 31_ LAGVP 36_ LTGMN 41_ PLSPY 46_ LNVDP 51_ RYLVQ 56_ DTDEF 61_ ILPTG 66_ ANKTR 71_ GRFEL 76_ AFFTI 81_ GGCCM 86_ TGAAF 91_ GAMNG 96_ LRLGL 101_ KETQN 106_ MAWSK 111_ PRNVQ 116_ ILNMV 121_ TRQGA 126_ LWANT 131_ LGSLA 136_ LLYSA 141_ FGVII 146_ EKTRG 151_ AEDDL 156_ NTVAA 161_ GTMTG 166_ MLYKC 171_ TGGLR 176_ GIARG 181_ GLTGL 186_ TLTSL 191_ YALYN 196_ NWEHM 201_KGSLL
1: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane (PubMed:10339406). Has a role in the activation of stress-induced mitophagy by protecting PINK1 from OMA1-mediated degradation and facilitating its accumulation at the outer mitochondrial membrane in response to depolarization (PubMed:37160114)