Gene name: UBE2L6

Uniprot entry:

O14933

Protein names:

Ubiquitin/ISG15-conjugating enzyme E2 L6 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme L6) (Retinoic acid-induced gene B protein) (RIG-B) (UbcH8) (Ubiquitin carrier protein L6) (Ubiquitin-protein ligase L6)

Protein sequence:

1_MMASM 6_ RVVKE 11_ LEDLQ 16_ KKPPP 21_ YLRNL 26_ SSDDA 31_ NVLVW 36_ HALLL 41_ PDQPP 46_ YHLKA 51_ FNLRI 56_ SFPPE 61_ YPFKP 66_ PMIKF 71_ TTKIY 76_ HPNVD 81_ ENGQI 86_ CLPII 91_ SSENW 96_ KPCTK 101_ TCQVL 106_ EALNV 111_ LVNRP 116_ NIREP 121_ LRMDL 126_ ADLLT 131_ QNPEL 136_ FRKNA 141_ EEFTL 146_RFGVD

Protein annotations

Protein functions:

1: Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3