Transcription factor EC (TFE-C) (Class E basic helix-loop-helix protein 34) (bHLHe34) (Transcription factor EC-like) (hTFEC-L)
1_MTLDH 6_ QIINP 11_ TLKWS 16_ QPAVP 21_ SGGPL 26_ VQHAH 31_ TTLDS 36_ DAGLT 41_ ENPLT 46_ KLLAI 51_ GKEDD 56_ NAQWH 61_ MEDVI 66_ EDIIG 71_ MESSF 76_ KEEGA 81_ DSPLL 86_ MQRTL 91_ SGSIL 96_ DVYSG 101_ EQGIS 106_ PINMG 111_ LTSAS 116_ CPSSL 121_ PMKRE 126_ ITETD 131_ TRALA 136_ KERQK 141_ KDNHN 146_ LIERR 151_ RRYNI 156_ NYRIK 161_ ELGTL 166_ IPKSN 171_ DPDMR 176_ WNKGT 181_ ILKAS 186_ VEYIK 191_ WLQKE 196_ QQRAR 201_ ELEHR 206_ QKKLE 211_ QANRR 216_ LLLRI 221_ QELEI 226_ QARTH 231_ GLPTL 236_ ASLGT 241_ VDLGA 246_ HVTKQ 251_ QSHPE 256_ QNSVD 261_ YCQQL 266_ TVSQG 271_ PSPEL 276_ CDQAI 281_ AFSDP 286_ LSYFT 291_ DLSFS 296_ AALKE 301_ EQRLD 306_ GMLLD 311_ DTISP 316_ FGTDP 321_ LLSAT 326_ SPAVS 331_ KESSR 336_ RSSFS 341_SDDGD
1: Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form