Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Cell migration-inducing gene 15 protein) (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-1) (Membrane lipid desaturase) (Retinol isomerase) (EC 5.2.1.-)
1_MGSRV 6_ SREDF 11_ EWVYT 16_ DQPHA 21_ DRRRE 26_ ILAKY 31_ PEIKS 36_ LMKPD 41_ PNLIW 46_ IIIMM 51_ VLTQL 56_ GAFYI 61_ VKDLD 66_ WKWVI 71_ FGAYA 76_ FGSCI 81_ NHSMT 86_ LAIHE 91_ IAHNA 96_ AFGNC 101_ KAMWN 106_ RWFGM 111_ FANLP 116_ IGIPY 121_ SISFK 126_ RYHMD 131_ HHRYL 136_ GADGV 141_ DVDIP 146_ TDFEG 151_ WFFCT 156_ AFRKF 161_ IWVIL 166_ QPLFY 171_ AFRPL 176_ FINPK 181_ PITYL 186_ EVINT 191_ VAQVT 196_ FDILI 201_ YYFLG 206_ IKSLV 211_ YMLAA 216_ SLLGL 221_ GLHPI 226_ SGHFI 231_ AEHYM 236_ FLKGH 241_ ETYSY 246_ YGPLN 251_ LLTFN 256_ VGYHN 261_ EHHDF 266_ PNIPG 271_ KSLPL 276_ VRKIA 281_ AEYYD 286_ NLPHY 291_ NSWIK 296_ VLYDF 301_ VMDDT 306_ ISPYS 311_ RMKRH 316_QKGEM
1: Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (PubMed:11937514, PubMed:30620337, PubMed:30620338). Catalyzes the equilibrium isomerization of retinols (By similarity)