DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40)
1_MAASQ 6_ AVEEM 11_ RSRVV 16_ LGEFG 21_ VRNVH 26_ TTDFP 31_ GNYSG 36_ YDDAW 41_ DQDRF 46_ EKNFR 51_ VDVVH 56_ MDENS 61_ LEFDM 66_ VGIDA 71_ AIANA 76_ FRRIL 81_ LAEVP 86_ TMAVE 91_ KVLVY 96_ NNTSI 101_ VQDEI 106_ LAHRL 111_ GLIPI 116_ HADPR 121_ LFEYR 126_ NQGDE 131_ EGTEI 136_ DTLQF 141_ RLQVR 146_ CTRNP 151_ HAAKD 156_ SSDPN 161_ ELYVN 166_ HKVYT 171_ RHMTW 176_ IPLGN 181_ QADLF 186_ PEGTI 191_ RPVHD 196_ DILIA 201_ QLRPG 206_ QEIDL 211_ LMHCV 216_ KGIGK 221_ DHAKF 226_ SPVAT 231_ ASYRL 236_ LPDIT 241_ LLEPV 246_ EGEAA 251_ EELSR 256_ CFSPG 261_ VIEVQ 266_ EVQGK 271_ KVARV 276_ ANPRL 281_ DTFSR 286_ EIFRN 291_ EKLKK 296_ VVRLA 301_ RVRDH 306_ YIFSV 311_ ESTGV 316_ LPPDV 321_ LVSEA 326_ IKVLM 331_ GKCRR 336_ FLDEL 341_DAVQM
1: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and short non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs, respectively. POLR1C/RPAC1 is part of the polymerase core and may function as a clamp element that moves to open and close the cleft