WD repeat-containing protein 46 (WD repeat-containing protein BING4)
1_METAP 6_ KPGKD 11_ VPPKK 16_ DKLQT 21_ KRKKP 26_ RRYWE 31_ EETVP 36_ TTAGA 41_ SPGPP 46_ RNKKN 51_ RELRP 56_ QRPKN 61_ AYILK 66_ KSRIS 71_ KKPQV 76_ PKKPR 81_ EWKNP 86_ ESQRG 91_ LSGTQ 96_ DPFPG 101_ PAPVP 106_ VEVVQ 111_ KFCRI 116_ DKSRK 121_ LPHSK 126_ AKTRS 131_ RLEVA 136_ EAEEE 141_ ETSIK 146_ AARSE 151_ LLLAE 156_ EPGFL 161_ EGEDG 166_ EDTAK 171_ ICQAD 176_ IVEAV 181_ DIASA 186_ AKHFD 191_ LNLRQ 196_ FGPYR 201_ LNYSR 206_ TGRHL 211_ AFGGR 216_ RGHVA 221_ ALDWV 226_ TKKLM 231_ CEINV 236_ MEAVR 241_ DIRFL 246_ HSEAL 251_ LAVAQ 256_ NRWLH 261_ IYDNQ 266_ GIELH 271_ CIRRC 276_ DRVTR 281_ LEFLP 286_ FHFLL 291_ ATASE 296_ TGFLT 301_ YLDVS 306_ VGKIV 311_ AALNA 316_ RAGRL 321_ DVMSQ 326_ NPYNA 331_ VIHLG 336_ HSNGT 341_ VSLWS 346_ PAMKE 351_ PLAKI 356_ LCHRG 361_ GVRAV 366_ AVDST 371_ GTYMA 376_ TSGLD 381_ HQLKI 386_ FDLRG 391_ TYQPL 396_ STRTL 401_ PHGAG 406_ HLAFS 411_ QRGLL 416_ VAGMG 421_ DVVNI 426_ WAGQG 431_ KASPP 436_ SLEQP 441_ YLTHR 446_ LSGPV 451_ HGLQF 456_ CPFED 461_ VLGVG 466_ HTGGI 471_ TSMLV 476_ PGAGE 481_ PNFDG 486_ LESNP 491_ YRSRK 496_ QRQEW 501_ EVKAL 506_ LEKVP 511_ AELIC 516_ LDPRA 521_ LAEVD 526_ VISLE 531_ QGKKE 536_ QIERL 541_ GYDPQ 546_ AKAPF 551_ QPKPK 556_ QKGRS 561_ STASL 566_ VKRKR 571_ KVMDE 576_ EHRDK 581_ VRQSL 586_ QQQHH 591_ KEAKA 596_ KPTGA 601_RPSAL
1: Scaffold component of the nucleolar structure. Required for localization of DDX21 and NCL to the granular compartment of the nucleolus (PubMed:23848194). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)