Metabotropic glutamate receptor 6 (mGluR6)
1_MARPR 6_ RAREP 11_ LLVAL 16_ LPLAW 21_ LAQAG 26_ LARAA 31_ GSVRL 36_ AGGLT 41_ LGGLF 46_ PVHAR 51_ GAAGR 56_ ACGQL 61_ KKEQG 66_ VHRLE 71_ AMLYA 76_ LDRVN 81_ ADPEL 86_ LPGVR 91_ LGARL 96_ LDTCS 101_ RDTYA 106_ LEQAL 111_ SFVQA 116_ LIRGR 121_ GDGDE 126_ VGVRC 131_ PGGVP 136_ PLRPA 141_ PPERV 146_ VAVVG 151_ ASASS 156_ VSIMV 161_ ANVLR 166_ LFAIP 171_ QISYA 176_ STAPE 181_ LSDST 186_ RYDFF 191_ SRVVP 196_ PDSYQ 201_ AQAMV 206_ DIVRA 211_ LGWNY 216_ VSTLA 221_ SEGNY 226_ GESGV 231_ EAFVQ 236_ ISREA 241_ GGVCI 246_ AQSIK 251_ IPREP 256_ KPGEF 261_ SKVIR 266_ RLMET 271_ PNARG 276_ IIIFA 281_ NEDDI 286_ RRVLE 291_ AARQA 296_ NLTGH 301_ FLWVG 306_ SDSWG 311_ AKTSP 316_ ILSLE 321_ DVAVG 326_ AITIL 331_ PKRAS 336_ IDGFD 341_ QYFMT 346_ RSLEN 351_ NRRNI 356_ WFAEF 361_ WEENF 366_ NCKLT 371_ SSGTQ 376_ SDDST 381_ RKCTG 386_ EERIG 391_ RDSTY 396_ EQEGK 401_ VQFVI 406_ DAVYA 411_ IAHAL 416_ HSMHQ 421_ ALCPG 426_ HTGLC 431_ PAMEP 436_ TDGRM 441_ LLQYI 446_ RAVRF 451_ NGSAG 456_ TPVMF 461_ NENGD 466_ APGRY 471_ DIFQY 476_ QATNG 481_ SASSG 486_ GYQAV 491_ GQWAE 496_ TLRLD 501_ VEALQ 506_ WSGDP 511_ HEVPS 516_ SLCSL 521_ PCGPG 526_ ERKKM 531_ VKGVP 536_ CCWHC 541_ EACDG 546_ YRFQV 551_ DEFTC 556_ EACPG 561_ DMRPT 566_ PNHTG 571_ CRPTP 576_ VVRLS 581_ WSSPW 586_ AAPPL 591_ LLAVL 596_ GIVAT 601_ TTVVA 606_ TFVRY 611_ NNTPI 616_ VRASG 621_ RELSY 626_ VLLTG 631_ IFLIY 636_ AITFL 641_ MVAEP 646_ GAAVC 651_ AARRL 656_ FLGLG 661_ TTLSY 666_ SALLT 671_ KTNRI 676_ YRIFE 681_ QGKRS 686_ VTPPP 691_ FISPT 696_ SQLVI 701_ TFSLT 706_ SLQVV 711_ GMIAW 716_ LGARP 721_ PHSVI 726_ DYEEQ 731_ RTVDP 736_ EQARG 741_ VLKCD 746_ MSDLS 751_ LIGCL 756_ GYSLL 761_ LMVTC 766_ TVYAI 771_ KARGV 776_ PETFN 781_ EAKPI 786_ GFTMY 791_ TTCII 796_ WLAFV 801_ PIFFG 806_ TAQSA 811_ EKIYI 816_ QTTTL 821_ TVSLS 826_ LSASV 831_ SLGML 836_ YVPKT 841_ YVILF 846_ HPEQN 851_ VQKRK 856_ RSLKA 861_ TSTVA 866_ APPKG 871_EDAEA
1: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision