Gene name: SIVA1

Uniprot entry:

O15304

Protein names:

Apoptosis regulatory protein Siva (CD27-binding protein) (CD27BP)

Protein sequence:

1_MPKRS 6_ CPFAD 11_ VAPLQ 16_ LKVRV 21_ SQREL 26_ SRGVC 31_ AERYS 36_ QEVFE 41_ KTKRL 46_ LFLGA 51_ QAYLD 56_ HVWDE 61_ GCAVV 66_ HLPES 71_ PKPGP 76_ TGAPR 81_ AARGQ 86_ MLIGP 91_ DGRLI 96_ RSLGQ 101_ ASEAD 106_ PSGVA 111_ SIACS 116_ SCVRA 121_ VDGKA 126_ VCGQC 131_ ERALC 136_ GQCVR 141_ TCWGC 146_ GSVAC 151_ TLCGL 156_ VDCSD 161_ MYEKV 166_LCTSC

Protein annotations

Protein functions:

1: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis