Tumor protein p73 (p53-like transcription factor) (p53-related protein)
1_MAQST 6_ ATSPD 11_ GGTTF 16_ EHLWS 21_ SLEPD 26_ STYFD 31_ LPQSS 36_ RGNNE 41_ VVGGT 46_ DSSMD 51_ VFHLE 56_ GMTTS 61_ VMAQF 66_ NLLSS 71_ TMDQM 76_ SSRAA 81_ SASPY 86_ TPEHA 91_ ASVPT 96_ HSPYA 101_ QPSST 106_ FDTMS 111_ PAPVI 116_ PSNTD 121_ YPGPH 126_ HFEVT 131_ FQQSS 136_ TAKSA 141_ TWTYS 146_ PLLKK 151_ LYCQI 156_ AKTCP 161_ IQIKV 166_ STPPP 171_ PGTAI 176_ RAMPV 181_ YKKAE 186_ HVTDV 191_ VKRCP 196_ NHELG 201_ RDFNE 206_ GQSAP 211_ ASHLI 216_ RVEGN 221_ NLSQY 226_ VDDPV 231_ TGRQS 236_ VVVPY 241_ EPPQV 246_ GTEFT 251_ TILYN 256_ FMCNS 261_ SCVGG 266_ MNRRP 271_ ILIII 276_ TLEMR 281_ DGQVL 286_ GRRSF 291_ EGRIC 296_ ACPGR 301_ DRKAD 306_ EDHYR 311_ EQQAL 316_ NESSA 321_ KNGAA 326_ SKRAF 331_ KQSPP 336_ AVPAL 341_ GAGVK 346_ KRRHG 351_ DEDTY 356_ YLQVR 361_ GRENF 366_ EILMK 371_ LKESL 376_ ELMEL 381_ VPQPL 386_ VDSYR 391_ QQQQL 396_ LQRPS 401_ HLQPP 406_ SYGPV 411_ LSPMN 416_ KVHGG 421_ MNKLP 426_ SVNQL 431_ VGQPP 436_ PHSSA 441_ ATPNL 446_ GPVGP 451_ GMLNN 456_ HGHAV 461_ PANGE 466_ MSSSH 471_ SAQSM 476_ VSGSH 481_ CTPPP 486_ PYHAD 491_ PSLVS 496_ FLTGL 501_ GCPNC 506_ IEYFT 511_ SQGLQ 516_ SIYHL 521_ QNLTI 526_ EDLGA 531_ LKIPE 536_ QYRMT 541_ IWRGL 546_ QDLKQ 551_ GHDYS 556_ TAQQL 561_ LRSSN 566_ AATIS 571_ IGGSG 576_ ELQRQ 581_ RVMEA 586_ VHFRV 591_ RHTIT 596_ IPNRG 601_ GPGGG 606_ PDEWA 611_ DFGFD 616_ LPDCK 621_ ARKQP 626_ IKEEF 631_TEAEI
1: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. Is an activator of FOXJ1 expression (By similarity). It is an essential factor for the positive regulation of lung ciliated cell differentiation (PubMed:34077761)