Gene name: TOX3

Uniprot entry:

O15405

Protein names:

TOX high mobility group box family member 3 (CAG trinucleotide repeat-containing gene F9 protein) (Trinucleotide repeat-containing gene 9 protein)

Protein sequence:

1_MDVRF 6_ YPAAA 11_ GDPAS 16_ LDFAQ 21_ CLGYY 26_ GYSKF 31_ GNNNN 36_ YMNMA 41_ EANNA 46_ FFAAS 51_ EQTFH 56_ TPSLG 61_ DEEFE 66_ IPPIT 71_ PPPES 76_ DPALG 81_ MPDVL 86_ LPFQA 91_ LSDPL 96_ PSQGS 101_ EFTPQ 106_ FPPQS 111_ LDLPS 116_ ITISR 121_ NLVEQ 126_ DGVLH 131_ SSGLH 136_ MDQSH 141_ TQVSQ 146_ YRQDP 151_ SLIMR 156_ SIVHM 161_ TDAAR 166_ SGVMP 171_ PAQLT 176_ TINQS 181_ QLSAQ 186_ LGLNL 191_ GGASM 196_ PHTSP 201_ SPPAS 206_ KSATP 211_ SPSSS 216_ INEED 221_ ADEAN 226_ RAIGE 231_ KRAAP 236_ DSGKK 241_ PKTPK 246_ KKKKK 251_ DPNEP 256_ QKPVS 261_ AYALF 266_ FRDTQ 271_ AAIKG 276_ QNPNA 281_ TFGEV 286_ SKIVA 291_ SMWDS 296_ LGEEQ 301_ KQVYK 306_ RKTEA 311_ AKKEY 316_ LKALA 321_ AYRAS 326_ LVSKA 331_ AAESA 336_ EAQTI 341_ RSVQQ 346_ TLAST 351_ NLTSS 356_ LLLNT 361_ PLSQH 366_ GTVSA 371_ SPQTL 376_ QQSLP 381_ RSIAP 386_ KPLTM 391_ RLPMN 396_ QIVTS 401_ VTIAA 406_ NMPSN 411_ IGAPL 416_ ISSMG 421_ TTMVG 426_ SAPST 431_ QVSPS 436_ VQTQQ 441_ HQMQL 446_ QQQQQ 451_ QQQQQ 456_ MQQMQ 461_ QQQLQ 466_ QHQMH 471_ QQIQQ 476_ QMQQQ 481_ HFQHH 486_ MQQHL 491_ QQQQQ 496_ HLQQQ 501_ INQQQ 506_ LQQQL 511_ QQRLQ 516_ LQQLQ 521_ HMQHQ 526_ SQPSP 531_ RQHSP 536_ VASQI 541_ TSPIP 546_ AIGSP 551_ QPASQ 556_ QHQSQ 561_ IQSQT 566_ QTQVL 571_SQVSI

Protein annotations

Protein functions:

1: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region