Regulator of G-protein signaling 16 (RGS16) (A28-RGS14P) (Retinal-specific RGS) (RGS-r) (hRGS-r) (Retinally abundant regulator of G-protein signaling)
1_MCRTL 6_ AAFPT 11_ TCLER 16_ AKEFK 21_ TRLGI 26_ FLHKS 31_ ELGCD 36_ TGSTG 41_ KFEWG 46_ SKHSK 51_ ENRNF 56_ SEDVL 61_ GWRES 66_ FDLLL 71_ SSKNG 76_ VAAFH 81_ AFLKT 86_ EFSEE 91_ NLEFW 96_ LACEE 101_ FKKIR 106_ SATKL 111_ ASRAH 116_ QIFEE 121_ FICSE 126_ APKEV 131_ NIDHE 136_ THELT 141_ RMNLQ 146_ TATAT 151_ CFDAA 156_ QGKTR 161_ TLMEK 166_ DSYPR 171_ FLKSP 176_ AYRDL 181_ AAQAS 186_ AASAT 191_ LSSCS 196_LDEPS
1: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11602604, PubMed:18434541). Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals (By similarity)