Retinoschisin (X-linked juvenile retinoschisis protein)
1_MSRKI 6_ EGFLL 11_ LLLFG 16_ YEATL 21_ GLSST 26_ EDEGE 31_ DPWYQ 36_ KACKC 41_ DCQGG 46_ PNALW 51_ SAGAT 56_ SLDCI 61_ PECPY 66_ HKPLG 71_ FESGE 76_ VTPDQ 81_ ITCSN 86_ PEQYV 91_ GWYSS 96_ WTANK 101_ ARLNS 106_ QGFGC 111_ AWLSK 116_ FQDSS 121_ QWLQI 126_ DLKEI 131_ KVISG 136_ ILTQG 141_ RCDID 146_ EWMTK 151_ YSVQY 156_ RTDER 161_ LNWIY 166_ YKDQT 171_ GNNRV 176_ FYGNS 181_ DRTST 186_ VQNLL 191_ RPPII 196_ SRFIR 201_ LIPLG 206_ WHVRI 211_ AIRME 216_LLECV
1: Binds negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides (By similarity). May play a role in cell-cell adhesion processes in the retina, via homomeric interaction between octamers present on the surface of two neighboring cells (PubMed:27114531). Required for normal structure and function of the retina (PubMed:19093009)