Endogenous retrovirus group K member 18 Env polyprotein (Envelope polyprotein) (HERV-K(C1a) envelope protein) (HERV-K110 envelope protein) (HERV-K18 envelope protein) (HERV-K18 superantigen) (HERV-K_1q23.3 provirus ancestral Env polyprotein) (IDDMK1,2 22 envelope protein) (IDDMK1,2 22 superantigen) [Cleaved into: Surface protein (SU); Transmembrane protein (TM)]
1_MVTPV 6_ TWMDN 11_ PIEVY 16_ VNDSV 21_ WVPGP 26_ TDDRC 31_ PAKPE 36_ EEGMM 41_ INISI 46_ GYHYP 51_ PICLG 56_ RAPGC 61_ LMPAV 66_ QNWLV 71_ EVPTV 76_ SPNSR 81_ FTYHM 86_ VSGMS 91_ LRPRV 96_ NCLQD 101_ FSYQR 106_ SLKFR 111_ PKGKT 116_ CPKEI 121_ PKGSK 126_ NTEVL 131_ VWEEC 136_ VANSV 141_ VILQN 146_ NEFGT 151_ IIDWA 156_ PRGQF 161_ YHNCS 166_ GQTQS 171_ CPSAQ 176_ VSPAV 181_ DSDLT 186_ ESLDK 191_ HKHKK 196_ LQSFY 201_ LWEWE 206_ EKGIS 211_ TPRPK 216_ IISPV 221_ SGPEH 226_ PELWR 231_ LTVAS 236_ HHIRI 241_ WSGNQ 246_ TLETR 251_ YRKPF 256_ YTIDL 261_ NSILT 266_ VPLQS 271_ CVKPP 276_ YMLVV 281_ GNIVI 286_ KPASQ 291_ TITCE 296_ NCRLF 301_ TCIDS 306_ TFNWQ 311_ HRILL 316_ VRARE 321_ GMWIP 326_ VSTDR 331_ PWEAS 336_ PSIHI 341_ LTEIL 346_ KGVLN 351_ RSKRF 356_ IFTLI 361_ AVIMG 366_ LIAVT 371_ ATAAV 376_ AGVAL 381_ HSSVQ 386_ SVNFV 391_ NYWQK 396_ NSTRL 401_ WNSQS 406_ SIDQK 411_ LASQI 416_ NDLRQ 421_ TVIWM 426_ GDRLM 431_ TLEHH 436_ FQLQC 441_ DWNTS 446_ DFCIT 451_ PQIYN 456_ ESEHH 461_ WDMVR 466_ RHLQG 471_ REDNL 476_ TLDIS 481_ KLKEQ 486_ IFEAS 491_ KAHLN 496_ LVPGT 501_ EAIAG 506_ VADGL 511_ ANLNP 516_ VTWIK 521_ TIRST 526_ MIINL 531_ ILIVV 536_ CLFCL 541_ LLVCR 546_ CTQQL 551_RRDSD
1: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This envelope protein has superantigenic properties
2: SU mediates receptor recognition
3: TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity)