mRNA cap guanine-N7 methyltransferase (EC 2.1.1.56) (RG7MT1) (mRNA (guanine-N(7))-methyltransferase) (mRNA cap methyltransferase) (hCMT1) (hMet) (hcm1p)
1_MANSA 6_ KAEEY 11_ EKMSL 16_ EQAKA 21_ SVNSE 26_ TESSF 31_ NINEN 36_ TTASG 41_ TGLSE 46_ KTSVC 51_ RQVDI 56_ ARKRK 61_ EFEDD 66_ LVKES 71_ SSCGK 76_ DTPSK 81_ KRKLD 86_ PEIVP 91_ EEKDC 96_ GDAEG 101_ NSKKR 106_ KRETE 111_ DVPKD 116_ KSSTG 121_ DGTQN 126_ KRKIA 131_ LEDVP 136_ EKQKN 141_ LEEGH 146_ SSTVA 151_ AHYNE 156_ LQEVG 161_ LEKRS 166_ QSRIF 171_ YLRNF 176_ NNWMK 181_ SVLIG 186_ EFLEK 191_ VRQKK 196_ KRDIT 201_ VLDLG 206_ CGKGG 211_ DLLKW 216_ KKGRI 221_ NKLVC 226_ TDIAD 231_ VSVKQ 236_ CQQRY 241_ EDMKN 246_ RRDSE 251_ YIFSA 256_ EFITA 261_ DSSKE 266_ LLIDK 271_ FRDPQ 276_ MCFDI 281_ CSCQF 286_ VCHYS 291_ FESYE 296_ QADMM 301_ LRNAC 306_ ERLSP 311_ GGYFI 316_ GTTPN 321_ SFELI 326_ RRLEA 331_ SETES 336_ FGNEI 341_ YTVKF 346_ QKKGD 351_ YPLFG 356_ CKYDF 361_ NLEGV 366_ VDVPE 371_ FLVYF 376_ PLLNE 381_ MAKKY 386_ NMKLV 391_ YKKTF 396_ LEFYE 401_ EKIKN 406_ NENKM 411_ LLKRM 416_ QALEP 421_ YPANE 426_ SSKLV 431_ SEKVD 436_ DYEHA 441_ AKYMK 446_ NSQVR 451_ LPLGT 456_ LSKSE 461_ WEATS 466_ IYLVF 471_AFEKQ
1: Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs (PubMed:10347220, PubMed:11114884, PubMed:22099306, PubMed:27422871, PubMed:9705270, PubMed:9790902). Binds RNA containing 5'-terminal GpppC (PubMed:11114884)