Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (Development and differentiation-enhancing factor 2) (Paxillin-associated protein with ARF GAP activity 3) (PAG3) (Pyk2 C-terminus-associated protein) (PAP)
1_MPDQI 6_ SVSEF 11_ VAETH 16_ EDYKA 21_ PTASS 26_ FTTRT 31_ AQCRN 36_ TVAAI 41_ EEALD 46_ VDRMV 51_ LYKMK 56_ KSVKA 61_ INSSG 66_ LAHVE 71_ NEEQY 76_ TQALE 81_ KFGGN 86_ CVCRD 91_ DPDLG 96_ SAFLK 101_ FSVFT 106_ KELTA 111_ LFKNL 116_ IQNMN 121_ NIISF 126_ PLDSL 131_ LKGDL 136_ KGVKG 141_ DLKKP 146_ FDKAW 151_ KDYET 156_ KITKI 161_ EKEKK 166_ EHAKL 171_ HGMIR 176_ TEISG 181_ AEIAE 186_ EMEKE 191_ RRFFQ 196_ LQMCE 201_ YLLKV 206_ NEIKI 211_ KKGVD 216_ LLQNL 221_ IKYFH 226_ AQCNF 231_ FQDGL 236_ KAVES 241_ LKPSI 246_ ETLST 251_ DLHTI 256_ KQAQD 261_ EERRQ 266_ LIQLR 271_ DILKS 276_ ALQVE 281_ QKEDS 286_ QIRQS 291_ TAYSL 296_ HQPQG 301_ NKEHG 306_ TERNG 311_ SLYKK 316_ SDGIR 321_ KVWQK 326_ RKCSV 331_ KNGFL 336_ TISHG 341_ TANRP 346_ PAKLN 351_ LLTCQ 356_ VKTNP 361_ EEKKC 366_ FDLIS 371_ HDRTY 376_ HFQAE 381_ DEQEC 386_ QIWMS 391_ VLQNS 396_ KEEAL 401_ NNAFK 406_ GDDNT 411_ GENNI 416_ VQELT 421_ KEIIS 426_ EVQRM 431_ TGNDV 436_ CCDCG 441_ APDPT 446_ WLSTN 451_ LGILT 456_ CIECS 461_ GIHRE 466_ LGVHY 471_ SRMQS 476_ LTLDV 481_ LGTSE 486_ LLLAK 491_ NIGNA 496_ GFNEI 501_ MECCL 506_ PAEDS 511_ VKPNP 516_ GSDMN 521_ ARKDY 526_ ITAKY 531_ IERRY 536_ ARKKH 541_ ADNAA 546_ KLHSL 551_ CEAVK 556_ TRDIF 561_ GLLQA 566_ YADGV 571_ DLTEK 576_ IPLAN 581_ GHEPD 586_ ETALH 591_ LAVRS 596_ VDRTS 601_ LHIVD 606_ FLVQN 611_ SGNLD 616_ KQTGK 621_ GSTAL 626_ HYCCL 631_ TDNAE 636_ CLKLL 641_ LRGKA 646_ SIEIA 651_ NESGE 656_ TPLDI 661_ AKRLK 666_ HEHCE 671_ ELLTQ 676_ ALSGR 681_ FNSHV 686_ HVEYE 691_ WRLLH 696_ EDLDE 701_ SDDDM 706_ DEKLQ 711_ PSPNR 716_ REDRP 721_ ISFYQ 726_ LGSNQ 731_ LQSNA 736_ VSLAR 741_ DAANL 746_ AKEKQ 751_ RAFMP 756_ SILQN 761_ ETYGA 766_ LLSGS 771_ PPPAQ 776_ PAAPS 781_ TTSAP 786_ PLPPR 791_ NVGKV 796_ QTASS 801_ ANTLW 806_ KTNSV 811_ SVDGG 816_ SRQRS 821_ SSDPP 826_ AVHPP 831_ LPPLR 836_ VTSTN 841_ PLTPT 846_ PPPPV 851_ AKTPS 856_ VMEAL 861_ SQPSK 866_ PAPPG 871_ ISQIR 876_ PPPLP 881_ PQPPS 886_ RLPQK 891_ KPAPG 896_ ADKST 901_ PLTNK 906_ GQPRG 911_ PVDLS 916_ ATEAL 921_ GPLSN 926_ AMVLQ 931_ PPAPM 936_ PRKSQ 941_ ATKLK 946_ PKRVK 951_ ALYNC 956_ VADNP 961_ DELTF 966_ SEGDV 971_ IIVDG 976_ EEDQE 981_ WWIGH 986_ IDGDP 991_ GRKGA 996_ FPVSF 1001_VHFIA
1: Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration