Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin-like domain-containing leucine-rich transmembrane protein 2)
1_MGLQT 6_ TKWPS 11_ HGAFF 16_ LKSWL 21_ IISLG 26_ LYSQV 31_ SKLLA 36_ CPSVC 41_ RCDRN 46_ FVYCN 51_ ERSLT 56_ SVPLG 61_ IPEGV 66_ TVLYL 71_ HNNQI 76_ NNAGF 81_ PAELH 86_ NVQSV 91_ HTVYL 96_ YGNQL 101_ DEFPM 106_ NLPKN 111_ VRVLH 116_ LQENN 121_ IQTIS 126_ RAALA 131_ QLLKL 136_ EELHL 141_ DDNSI 146_ STVGV 151_ EDGAF 156_ REAIS 161_ LKLLF 166_ LSKNH 171_ LSSVP 176_ VGLPV 181_ DLQEL 186_ RVDEN 191_ RIAVI 196_ SDMAF 201_ QNLTS 206_ LERLI 211_ VDGNL 216_ LTNKG 221_ IAEGT 226_ FSHLT 231_ KLKEF 236_ SIVRN 241_ SLSHP 246_ PPDLP 251_ GTHLI 256_ RLYLQ 261_ DNQIN 266_ HIPLT 271_ AFSNL 276_ RKLER 281_ LDISN 286_ NQLRM 291_ LTQGV 296_ FDNLS 301_ NLKQL 306_ TARNN 311_ PWFCD 316_ CSIKW 321_ VTEWL 326_ KYIPS 331_ SLNVR 336_ GFMCQ 341_ GPEQV 346_ RGMAV 351_ RELNM 356_ NLLSC 361_ PTTTP 366_ GLPLF 371_ TPAPS 376_ TASPT 381_ TQPPT 386_ LSIPN 391_ PSRSY 396_ TPPTP 401_ TTSKL 406_ PTIPD 411_ WDGRE 416_ RVTPP 421_ ISERI 426_ QLSIH 431_ FVNDT 436_ SIQVS 441_ WLSLF 446_ TVMAY 451_ KLTWV 456_ KMGHS 461_ LVGGI 466_ VQERI 471_ VSGEK 476_ QHLSL 481_ VNLEP 486_ RSTYR 491_ ICLVP 496_ LDAFN 501_ YRAVE 506_ DTICS 511_ EATTH 516_ ASYLN 521_ NGSNT 526_ ASSHE 531_ QTTSH 536_ SMGSP 541_ FLLAG 546_ LIGGA 551_ VIFVL 556_ VVLLS 561_ VFCWH 566_ MHKKG 571_ RYTSQ 576_ KWKYN 581_ RGRRK 586_ DDYCE 591_ AGTKK 596_ DNSIL 601_ EMTET 606_ SFQIV 611_ SLNND 616_ QLLKG 621_ DFRLQ 626_ PIYTP 631_ NGGIN 636_ YTDCH 641_ IPNNM 646_ RYCNS 651_SVPDL
1: Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis