Centromere/kinetochore protein zw10 homolog
1_MASFV 6_ TEVLA 11_ HSGRL 16_ EKEDL 21_ GTRIS 26_ RLTRR 31_ VEEIK 36_ GEVCN 41_ MISKK 46_ YSEFL 51_ PSMQS 56_ AQGLI 61_ TQVDK 66_ LSEDI 71_ DLLKS 76_ RIESE 81_ VRRDL 86_ HVSTG 91_ EFTDL 96_ KQQLE 101_ RDSVV 106_ LSLLK 111_ QLQEF 116_ STAIE 121_ EYNCA 126_ LTEKK 131_ YVTGA 136_ QRLEE 141_ AQKCL 146_ KLLKS 151_ RKCFD 156_ LKILK 161_ SLSME 166_ LTIQK 171_ QNILY 176_ HLGEE 181_ WQKLI 186_ VWKFP 191_ PSKDT 196_ SSLES 201_ YLQTE 206_ LHLYT 211_ EQSHK 216_ EEKTP 221_ MPPIS 226_ SVLLA 231_ FSVLG 236_ ELHSK 241_ LKSFG 246_ QMLLK 251_ YILRP 256_ LASCP 261_ SLHAV 266_ IESQP 271_ NIVII 276_ RFESI 281_ MTNLE 286_ YPSPS 291_ EVFTK 296_ IRLVL 301_ EVLQK 306_ QLLDL 311_ PLDTD 316_ LENEK 321_ TSTVP 326_ LAEML 331_ GDMIW 336_ EDLSE 341_ CLIKN 346_ CLVYS 351_ IPTNS 356_ SKLQQ 361_ YEEII 366_ QSTEE 371_ FENAL 376_ KEMRF 381_ LKGDT 386_ TDLLK 391_ YARNI 396_ NSHFA 401_ NKKCQ 406_ DVIVA 411_ ARNLM 416_ TSEIH 421_ NTVKI 426_ IPDSK 431_ INVPE 436_ LPTPD 441_ EDNKL 446_ EVQKV 451_ SNTQY 456_ HEVMN 461_ LEPEN 466_ TLDQH 471_ SFSLP 476_ TCRIS 481_ ESVKK 486_ LMELA 491_ YQTLL 496_ EATTS 501_ SDQCA 506_ VQLFY 511_ SVRNI 516_ FHLFH 521_ DVVPT 526_ YHKEN 531_ LQKLP 536_ QLAAI 541_ HHNNC 546_ MYIAH 551_ HLLTL 556_ GHQFR 561_ LRLAP 566_ ILCDG 571_ TATFV 576_ DLVPG 581_ FRRLG 586_ TECFL 591_ AQMRA 596_ QKGEL 601_ LERLS 606_ SARNF 611_ SNMDD 616_ EENYS 621_ AASKA 626_ VRQVL 631_ HQLKR 636_ LGIVW 641_ QDVLP 646_ VNIYC 651_ KAMGT 656_ LLNTA 661_ ISEVI 666_ GKITA 671_ LEDIS 676_ TEDGD 681_ RLYSL 686_ CKTVM 691_ DEGPQ 696_ VFAPL 701_ SEESK 706_ NKKYQ 711_ EEVPV 716_ YVPKW 721_ MPFKE 726_ LMMML 731_ QASLQ 736_ EIGDR 741_ WADGK 746_ GPLAA 751_ AFSSS 756_ EVKAL 761_ IRALF 766_ QNTER 771_RAAAL
1: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:11590237, PubMed:15485811, PubMed:15824131). Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER (PubMed:15029241)