Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin)
1_MAQLC 6_ GLRRS 11_ RAFLA 16_ LLGSL 21_ LLSGV 26_ LAADR 31_ ERSIH 36_ DFCLV 41_ SKVVG 46_ RCRAS 51_ MPRWW 56_ YNVTD 61_ GSCQL 66_ FVYGG 71_ CDGNS 76_ NNYLT 81_ KEECL 86_ KKCAT 91_ VTENA 96_ TGDLA 101_ TSRNA 106_ ADSSV 111_ PSAPR 116_ RQDSE 121_ DHSSD 126_ MFNYE 131_ EYCTA 136_ NAVTG 141_ PCRAS 146_ FPRWY 151_ FDVER 156_ NSCNN 161_ FIYGG 166_ CRGNK 171_ NSYRS 176_ EEACM 181_ LRCFR 186_ QQENP 191_ PLPLG 196_ SKVVV 201_ LAGLF 206_ VMVLI 211_ LFLGA 216_ SMVYL 221_ IRVAR 226_ RNQER 231_ ALRTV 236_ WSSGD 241_ DKEQL 246_VKNTY
1: Inhibitor of HGFAC (PubMed:9346890). Also inhibits plasmin, and plasma and tissue kallikrein (PubMed:9115294). Inhibits serine protease activity of TMPRSS13 (PubMed:20977675, PubMed:28710277). Inhibits serine protease activity of ST14/matriptase and PRSS8/prostasin in vitro (PubMed:28710277, PubMed:30445423)