Mediator of RNA polymerase II transcription subunit 7 (hMED7) (Activator-recruited cofactor 34 kDa component) (ARC34) (Cofactor required for Sp1 transcriptional activation subunit 9) (CRSP complex subunit 9) (Mediator complex subunit 7) (RNA polymerase transcriptional regulation mediator subunit 7 homolog) (Transcriptional coactivator CRSP33)
1_MGEPQ 6_ QVSAL 11_ PPPPM 16_ QYIKE 21_ YTDEN 26_ IQEGL 31_ APKPP 36_ PPIKD 41_ SYMMF 46_ GNQFQ 51_ CDDLI 56_ IRPLE 61_ SQGIE 66_ RLHPM 71_ QFDHK 76_ KELRK 81_ LNMSI 86_ LINFL 91_ DLLDI 96_ LIRSP 101_ GSIKR 106_ EEKLE 111_ DLKLL 116_ FVHVH 121_ HLINE 126_ YRPHQ 131_ ARETL 136_ RVMME 141_ VQKRQ 146_ RLETA 151_ ERFQK 156_ HLERV 161_ IEMIQ 166_ NCLAS 171_ LPDDL 176_ PHSEA 181_ GMRVK 186_ TEPMD 191_ ADDSN 196_ NCTGQ 201_ NEHQR 206_ ENSGH 211_ RRDQI 216_ IEKDA 221_ ALCVL 226_IDEMN
1: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors