WAS/WASL-interacting protein family member 1 (Protein PRPL-2) (Wiskott-Aldrich syndrome protein-interacting protein) (WASP-interacting protein)
1_MPVPP 6_ PPAPP 11_ PPPTF 16_ ALANT 21_ EKPTL 26_ NKTEQ 31_ AGRNA 36_ LLSDI 41_ SKGKK 46_ LKKTV 51_ TNDRS 56_ APILD 61_ KPKGA 66_ GAGGG 71_ GGGFG 76_ GGGGF 81_ GGGGG 86_ GGGGG 91_ SFGGG 96_ GPPGL 101_ GGLFQ 106_ AGMPK 111_ LRSTA 116_ NRDND 121_ SGGSR 126_ PPLLP 131_ PGGRS 136_ TSAKP 141_ FSPPS 146_ GPGRF 151_ PVPSP 156_ GHRSG 161_ PPEPQ 166_ RNRMP 171_ PPRPD 176_ VGSKP 181_ DSIPP 186_ PVPST 191_ PRPIQ 196_ SSPHN 201_ RGSPP 206_ VPGGP 211_ RQPSP 216_ GPTPP 221_ PFPGN 226_ RGTAL 231_ GGGSI 236_ RQSPL 241_ SSSSP 246_ FSNRP 251_ PLPPT 256_ PSRAL 261_ DDKPP 266_ PPPPP 271_ VGNRP 276_ SIHRE 281_ AVPPP 286_ PPQNN 291_ KPPVP 296_ STPRP 301_ SASSQ 306_ APPPP 311_ PPPSR 316_ PGPPP 321_ LPPSS 326_ SGNDE 331_ TPRLP 336_ QRNLS 341_ LSSST 346_ PPLPS 351_ PGRSG 356_ PLPPP 361_ PSERP 366_ PPPVR 371_ DPPGR 376_ SGPLP 381_ PPPPV 386_ SRNGS 391_ TSRAL 396_ PATPQ 401_ LPSRS 406_ GVDSP 411_ RSGPR 416_ PPLPP 421_ DRPSA 426_ GAPPP 431_ PPPST 436_ SIRNG 441_ FQDSP 446_ CEDEW 451_ ESRFY 456_ FHPIS 461_ DLPPP 466_ EPYVQ 471_ TTKSY 476_ PSKLA 481_ RNESR 486_ SGSNR 491_ RERGA 496_PPLPP
1: Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation. Plays a role in the formation of cell ruffles (By similarity). Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus