Bcl-2-like protein 11 (Bcl2-L-11) (Bcl2-interacting mediator of cell death)
1_MAKQP 6_ SDVSS 11_ ECDRE 16_ GRQLQ 21_ PAERP 26_ PQLRP 31_ GAPTS 36_ LQTEP 41_ QGNPE 46_ GNHGG 51_ EGDSC 56_ PHGSP 61_ QGPLA 66_ PPASP 71_ GPFAT 76_ RSPLF 81_ IFMRR 86_ SSLLS 91_ RSSSG 96_ YFSFD 101_ TDRSP 106_ APMSC 111_ DKSTQ 116_ TPSPP 121_ CQAFN 126_ HYLSA 131_ MASMR 136_ QAEPA 141_ DMRPE 146_ IWIAQ 151_ ELRRI 156_ GDEFN 161_ AYYAR 166_ RVFLN 171_ NYQAA 176_ EDHPR 181_ MVILR 186_ LLRYI 191_VRLVW
1: Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis