Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
1_MTEEV 6_ IVIAK 11_ WDYTA 16_ QQDQE 21_ LDIKK 26_ NERLW 31_ LLDDS 36_ KTWWR 41_ VRNAA 46_ NRTGY 51_ VPSNY 56_ VERKN 61_ SLKKG 66_ SLVKN 71_ LKDTL 76_ GLGKT 81_ RRKTS 86_ ARDAS 91_ PTPST 96_ DAEYP 101_ ANGSG 106_ ADRIY 111_ DLNIP 116_ AFVKF 121_ AYVAE 126_ REDEL 131_ SLVKG 136_ SRVTV 141_ MEKCS 146_ DGWWR 151_ GSYNG 156_ QIGWF 161_ PSNYV 166_ LEEVD 171_ EAAAE 176_ SPSFL 181_ SLRKG 186_ ASLSN 191_ GQGSR 196_ VLHVV 201_ QTLYP 206_ FSSVT 211_ EEELN 216_ FEKGE 221_ TMEVI 226_ EKPEN 231_ DPEWW 236_ KCKNA 241_ RGQVG 246_ LVPKN 251_ YVVVL 256_ SDGPA 261_ LHPAH 266_ APQIS 271_ YTGPS 276_ SSGRF 281_ AGREW 286_ YYGNV 291_ TRHQA 296_ ECALN 301_ ERGVE 306_ GDFLI 311_ RDSES 316_ SPSDF 321_ SVSLK 326_ ASGKN 331_ KHFKV 336_ QLVDN 341_ VYCIG 346_ QRRFH 351_ TMDEL 356_ VEHYK 361_ KAPIF 366_ TSEHG 371_EKLYL
1: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling