A-kinase anchor protein 7 isoforms alpha and beta (AKAP-7 isoforms alpha and beta) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoforms alpha/beta) (PRKA7 isoforms alpha/beta)
1_MGQLC 6_ CFPFS 11_ RDEGK 16_ ISELE 21_ SSSSA 26_ VLQRY 31_ SKDIP 36_ SWSSG 41_ EKNGG 46_ EPDDA 51_ ELVRL 56_ SKRLV 61_ ENAVL 66_ KAVQQ 71_ YLEET 76_ QNKNK 81_ PGEGS 86_ SVKTE 91_ AADQN 96_GNDNE
1: Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium