T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Neural crest homeobox protein)
1_MEPGM 6_ LGPHN 11_ LPHHE 16_ PISFG 21_ IDQIL 26_ SGPET 31_ PGGGL 36_ GLGRG 41_ GQGHG 46_ ENGAF 51_ SGGYH 56_ GASGY 61_ GPAGS 66_ LAPLP 71_ GSSGV 76_ GPGGV 81_ IRVPA 86_ HRPLP 91_ VPPPA 96_ GGAPA 101_ VPGPS 106_ GLGGA 111_ GGLAG 116_ LTFPW 121_ MDSGR 126_ RFAKD 131_ RLTAA 136_ LSPFS 141_ GTRRI 146_ GHPYQ 151_ NRTPP 156_ KRKKP 161_ RTSFS 166_ RSQVL 171_ ELERR 176_ FLRQK 181_ YLASA 186_ ERAAL 191_ AKALR 196_ MTDAQ 201_ VKTWF 206_ QNRRT 211_ KWRRQ 216_ TAEER 221_ EAERH 226_ RAGRL 231_ LLHLQ 236_ QDALP 241_ RPLRP 246_ PLPPD 251_ PLCLH 256_ NSSLF 261_ ALQNL 266_ QPWAE 271_ DNKVA 276_SVSGL
1: Transcription activator that binds DNA elements with the consensus sequence 5'-CGGTAATTGG-3'. Binds DNA via its homeobox. Required for normal cell death of enteric neurons in the gastrointestinal tract. Required for normal development of the enteric nervous system, and for proper development of normal motility of the gastrointestinal tract (By similarity)