Gene name: SSNA1

Uniprot entry:

O43805

Protein names:

Sjoegren syndrome nuclear autoantigen 1 (Nuclear autoantigen of 14 kDa)

Protein sequence:

1_MTQQG 6_ AALQN 11_ YNNEL 16_ VKCIE 21_ ELCQK 26_ REELC 31_ RQIQE 36_ EEDEK 41_ QRLQN 46_ EVRQL 51_ TEKLA 56_ RVNEN 61_ LARKI 66_ ASRNE 71_ FDRTI 76_ AETEA 81_ AYLKI 86_ LESSQ 91_ TLLSV 96_ LKREA 101_ GNLTK 106_ ATAPD 111_QKSSG

Protein annotations

Protein functions:

1: Microtubule-binding protein which stabilizes dynamic microtubules by slowing growth and shrinkage at both plus and minus ends and serves as a sensor of microtubule damage, protecting microtubules from the microtubule-severing enzyme SPAST (PubMed:34970964). Induces microtubule branching which is mediated by the formation of long SSNA1 fibrils which guide microtubule protofilaments to split apart from the mother microtubule and form daughter microtubules (By similarity). Plays a role in axon outgrowth and branching (PubMed:25390646). Required for cell division (PubMed:25390646)