Protein SCO2 homolog, mitochondrial
1_MLLLT 6_ RSPTA 11_ WHRLS 16_ QLKPR 21_ VLPGT 26_ LGGQA 31_ LHLRS 36_ WLLSR 41_ QGPAE 46_ TGGQG 51_ QPQGP 56_ GLRTR 61_ LLITG 66_ LFGAG 71_ LGGAW 76_ LALRA 81_ EKERL 86_ QQQKR 91_ TEALR 96_ QAAVG 101_ QGDFH 106_ LLDHR 111_ GRARC 116_ KADFR 121_ GQWVL 126_ MYFGF 131_ THCPD 136_ ICPDE 141_ LEKLV 146_ QVVRQ 151_ LEAEP 156_ GLPPV 161_ QPVFI 166_ TVDPE 171_ RDDVE 176_ AMARY 181_ VQDFH 186_ PRLLG 191_ LTGST 196_ KQVAQ 201_ ASHSY 206_ RVYYN 211_ AGPKD 216_ EDQDY 221_ IVDHS 226_ IAIYL 231_ LNPDG 236_ LFTDY 241_ YGRSR 246_ SAEQI 251_ SDSVR 256_ RHMAA 261_FRSVL
1: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2) by facilitating the incorporation of copper into the Cu(A) site of MT-CO2/COX2 (PubMed:15229189, PubMed:17189203, PubMed:19336478). Could also act as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2 (PubMed:19336478)