Angiopoietin-related protein 7 (Angiopoietin-like factor) (Angiopoietin-like protein 7) (Cornea-derived transcript 6 protein)
1_MLKKP 6_ LSAVT 11_ WLCIF 16_ IVAFV 21_ SHPAW 26_ LQKLS 31_ KHKTP 36_ AQPQL 41_ KAANC 46_ CEEVK 51_ ELKAQ 56_ VANLS 61_ SLLSE 66_ LNKKQ 71_ ERDWV 76_ SVVMQ 81_ VMELE 86_ SNSKR 91_ MESRL 96_ TDAES 101_ KYSEM 106_ NNQID 111_ IMQLQ 116_ AAQTV 121_ TQTSA 126_ DAIYD 131_ CSSLY 136_ QKNYR 141_ ISGVY 146_ KLPPD 151_ DFLGS 156_ PELEV 161_ FCDME 166_ TSGGG 171_ WTIIQ 176_ RRKSG 181_ LVSFY 186_ RDWKQ 191_ YKQGF 196_ GSIRG 201_ DFWLG 206_ NEHIH 211_ RLSRQ 216_ PTRLR 221_ VEMED 226_ WEGNL 231_ RYAEY 236_ SHFVL 241_ GNELN 246_ SYRLF 251_ LGNYT 256_ GNVGN 261_ DALQY 266_ HNNTA 271_ FSTKD 276_ KDNDN 281_ CLDKC 286_ AQLRK 291_ GGYWY 296_ NCCTD 301_ SNLNG 306_ VYYRL 311_ GEHNK 316_ HLDGI 321_ TWYGW 326_ HGSTY 331_ SLKRV 336_ EMKIR 341_PEDFK
1: Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure (PubMed:21199193). Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency (PubMed:25622036)