Peroxisome biogenesis factor 1 (Peroxin-1) (Peroxisome biogenesis disorder protein 1)
1_MWGSD 6_ RLAGA 11_ GGGGA 16_ AVTVA 21_ FTNAR 26_ DCFLH 31_ LPRRL 36_ VAQLH 41_ LLQNQ 46_ AIEVV 51_ WSHQP 56_ AFLSW 61_ VEGRH 66_ FSDQG 71_ ENVAE 76_ INRQV 81_ GQKLG 86_ LSNGG 91_ QVFLK 96_ PCSHV 101_ VSCQQ 106_ VEVEP 111_ LSADD 116_ WEILE 121_ LHAVS 126_ LEQHL 131_ LDQIR 136_ IVFPK 141_ AIFPV 146_ WVDQQ 151_ TYIFI 156_ QIVAL 161_ IPAAS 166_ YGRLE 171_ TDTKL 176_ LIQPK 181_ TRRAK 186_ ENTFS 191_ KADAE 196_ YKKLH 201_ SYGRD 206_ QKGMM 211_ KELQT 216_ KQLQS 221_ NTVGI 226_ TESNE 231_ NESEI 236_ PVDSS 241_ SVASL 246_ WTMIG 251_ SIFSF 256_ QSEKK 261_ QETSW 266_ GLTEI 271_ NAFKN 276_ MQSKV 281_ VPLDN 286_ IFRVC 291_ KSQPP 296_ SIYNA 301_ SATSV 306_ FHKHC 311_ AIHVF 316_ PWDQE 321_ YFDVE 326_ PSFTV 331_ TYGKL 336_ VKLLS 341_ PKQQQ 346_ SKTKQ 351_ NVLSP 356_ EKEKQ 361_ MSEPL 366_ DQKKI 371_ RSDHN 376_ EEDEK 381_ ACVLQ 386_ VVWNG 391_ LEELN 396_ NAIKY 401_ TKNVE 406_ VLHLG 411_ KVWIP 416_ DDLRK 421_ RLNIE 426_ MHAVV 431_ RITPV 436_ EVTPK 441_ IPRSL 446_ KLQPR 451_ ENLPK 456_ DISEE 461_ DIKTV 466_ FYSWL 471_ QQSTT 476_ TMLPL 481_ VISEE 486_ EFIKL 491_ ETKDG 496_ LKEFS 501_ LSIVH 506_ SWEKE 511_ KDKNI 516_ FLLSP 521_ NLLQK 526_ TTIQV 531_ LLDPM 536_ VKEEN 541_ SEEID 546_ FILPF 551_ LKLSS 556_ LGGVN 561_ SLGVS 566_ SLEHI 571_ THSLL 576_ GRPLS 581_ RQLMS 586_ LVAGL 591_ RNGAL 596_ LLTGG 601_ KGSGK 606_ STLAK 611_ AICKE 616_ AFDKL 621_ DAHVE 626_ RVDCK 631_ ALRGK 636_ RLENI 641_ QKTLE 646_ VAFSE 651_ AVWMQ 656_ PSVVL 661_ LDDLD 666_ LIAGL 671_ PAVPE 676_ HEHSP 681_ DAVQS 686_ QRLAH 691_ ALNDM 696_ IKEFI 701_ SMGSL 706_ VALIA 711_ TSQSQ 716_ QSLHP 721_ LLVSA 726_ QGVHI 731_ FQCVQ 736_ HIQPP 741_ NQEQR 746_ CEILC 751_ NVIKN 756_ KLDCD 761_ INKFT 766_ DLDLQ 771_ HVAKE 776_ TGGFV 781_ ARDFT 786_ VLVDR 791_ AIHSR 796_ LSRQS 801_ ISTRE 806_ KLVLT 811_ TLDFQ 816_ KALRG 821_ FLPAS 826_ LRSVN 831_ LHKPR 836_ DLGWD 841_ KIGGL 846_ HEVRQ 851_ ILMDT 856_ IQLPA 861_ KYPEL 866_ FANLP 871_ IRQRT 876_ GILLY 881_ GPPGT 886_ GKTLL 891_ AGVIA 896_ RESRM 901_ NFISV 906_ KGPEL 911_ LSKYI 916_ GASEQ 921_ AVRDI 926_ FIRAQ 931_ AAKPC 936_ ILFFD 941_ EFESI 946_ APRRG 951_ HDNTG 956_ VTDRV 961_ VNQLL 966_ TQLDG 971_ VEGLQ 976_ GVYVL 981_ AATSR 986_ PDLID 991_ PALLR 996_ PGRLD 1001_ KCVYC 1006_ PPPDQ 1011_ VSRLE 1016_ ILNVL 1021_ SDSLP 1026_ LADDV 1031_ DLQHV 1036_ ASVTD 1041_ SFTGA 1046_ DLKAL 1051_ LYNAQ 1056_ LEALH 1061_ GMLLS 1066_ SGLQD 1071_ GSSSS 1076_ DSDLS 1081_ LSSMV 1086_ FLNHS 1091_ SGSDD 1096_ SAGDG 1101_ ECGLD 1106_ QSLVS 1111_ LEMSE 1116_ ILPDE 1121_ SKFNM 1126_ YRLYF 1131_ GSSYE 1136_ SELGN 1141_ GTSSD 1146_ LSSQC 1151_ LSAPS 1156_ SMTQD 1161_ LPGVP 1166_ GKDQL 1171_ FSQPP 1176_ VLRTA 1181_ SQEGC 1186_ QELTQ 1191_ EQRDQ 1196_ LRADI 1201_ SIIKG 1206_ RYRSQ 1211_ SGEDE 1216_ SMNQP 1221_ GPIKT 1226_ RLAIS 1231_ QSHLM 1236_ TALGH 1241_ TRPSI 1246_ SEDDW 1251_ KNFAE 1256_ LYESF 1261_ QNPKR 1266_ RKNQS 1271_ GTMFR 1276_PGQKV
1: Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling (PubMed:11439091, PubMed:16314507, PubMed:16854980, PubMed:21362118, PubMed:29884772). Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel (PubMed:29884772). Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5 (PubMed:29884772)