Gene name: PSPN

Uniprot entry:

O60542

Protein names:

Persephin (PSP)

Protein sequence:

1_MAVGK 6_ FLLGS 11_ LLLLS 16_ LQLGQ 21_ GWGPD 26_ ARGVP 31_ VADGE 36_ FSSEQ 41_ VAKAG 46_ GTWLG 51_ THRPL 56_ ARLRR 61_ ALSGP 66_ CQLWS 71_ LTLSV 76_ AELGL 81_ GYASE 86_ EKVIF 91_ RYCAG 96_ SCPRG 101_ ARTQH 106_ GLALA 111_ RLQGQ 116_ GRAHG 121_ GPCCR 126_ PTRYT 131_ DVAFL 136_ DDRHR 141_ WQRLP 146_ QLSAA 151_ACGCG

Protein annotations

Protein functions:

1: Growth factor that exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons (PubMed:11116144, PubMed:9491986). Acts by binding to its coreceptor, GFRA4, leading to autophosphorylation and activation of the RET receptor (PubMed:11116144)