Gene name: GFRA3

Uniprot entry:

O60609

Protein names:

GDNF family receptor alpha-3 (GDNF receptor alpha-3) (GDNFR-alpha-3) (GFR-alpha-3)

Protein sequence:

1_MVRPL 6_ NPRPL 11_ PPVVL 16_ MLLLL 21_ LPPSP 26_ LPLAA 31_ GDPLP 36_ TESRL 41_ MNSCL 46_ QARRK 51_ CQADP 56_ TCSAA 61_ YHHLD 66_ SCTSS 71_ ISTPL 76_ PSEEP 81_ SVPAD 86_ CLEAA 91_ QQLRN 96_ SSLIG 101_ CMCHR 106_ RMKNQ 111_ VACLD 116_ IYWTV 121_ HRARS 126_ LGNYE 131_ LDVSP 136_ YEDTV 141_ TSKPW 146_ KMNLS 151_ KLNML 156_ KPDSD 161_ LCLKF 166_ AMLCT 171_ LNDKC 176_ DRLRK 181_ AYGEA 186_ CSGPH 191_ CQRHV 196_ CLRQL 201_ LTFFE 206_ KAAEP 211_ HAQGL 216_ LLCPC 221_ APNDR 226_ GCGER 231_ RRNTI 236_ APNCA 241_ LPPVA 246_ PNCLE 251_ LRRLC 256_ FSDPL 261_ CRSRL 266_ VDFQT 271_ HCHPM 276_ DILGT 281_ CATEQ 286_ SRCLR 291_ AYLGL 296_ IGTAM 301_ TPNFV 306_ SNVNT 311_ SVALS 316_ CTCRG 321_ SGNLQ 326_ EECEM 331_ LEGFF 336_ SHNPC 341_ LTEAI 346_ AAKMR 351_ FHSQL 356_ FSQDW 361_ PHPTF 366_ AVMAH 371_ QNENP 376_ AVRPQ 381_ PWVPS 386_ LFSCT 391_LPLIL

Protein annotations

Protein functions:

1: Receptor for artemin (ARTN), a growth factor that supports the survival of sensory and sympathetic peripheral neurons (PubMed:31535977, PubMed:9883723). ARTN-binding leads to autophosphorylation and activation of the RET receptor (PubMed:31535977, PubMed:9883723)