Sushi repeat-containing protein SRPX2 (Sushi-repeat protein upregulated in leukemia)
1_MASQL 6_ TQRGA 11_ LFLLF 16_ FLTPA 21_ VTPTW 26_ YAGSG 31_ YYPDE 36_ SYNEV 41_ YAEEV 46_ PQAPA 51_ LDYRV 56_ PRWCY 61_ TLNIQ 66_ DGEAT 71_ CYSPK 76_ GGNYH 81_ SSLGT 86_ RCELS 91_ CDRGF 96_ RLIGR 101_ RSVQC 106_ LPSRR 111_ WSGTA 116_ YCRQM 121_ RCHAL 126_ PFITS 131_ GTYTC 136_ TNGVL 141_ LDSRC 146_ DYSCS 151_ SGYHL 156_ EGDRS 161_ RICME 166_ DGRWS 171_ GGEPV 176_ CVDID 181_ PPKIR 186_ CPHSR 191_ EKMAE 196_ PEKLT 201_ ARVYW 206_ DPPLV 211_ KDSAD 216_ GTITR 221_ VTLRG 226_ PEPGS 231_ HFPEG 236_ EHVIR 241_ YTAYD 246_ RAYNR 251_ ASCKF 256_ IVKVQ 261_ VRRCP 266_ TLKPP 271_ QHGYL 276_ TCTSA 281_ GDNYG 286_ ATCEY 291_ HCDGG 296_ YDRQG 301_ TPSRV 306_ CQSSR 311_ QWSGS 316_ PPICA 321_ PMKIN 326_ VNVNS 331_ AAGLL 336_ DQFYE 341_ KQRLL 346_ IISAP 351_ DPSNR 356_ YYKMQ 361_ ISMLQ 366_ QSTCG 371_ LDLRH 376_ VTIIE 381_ LVGQP 386_ PQEVG 391_ RIREQ 396_ QLSAN 401_ IIEEL 406_ RQFQR 411_ LTRSY 416_ FNMVL 421_ IDKQG 426_ IDRDR 431_ YMEPV 436_ TPEEI 441_ FTFID 446_ DYLLS 451_ NQELT 456_QRREQ
1: Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. May have a role in the perisylvian region, critical for language and cognitive development