Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
1_MEGGG 6_ KPNSS 11_ SNSRD 16_ DGNSV 21_ FPAKA 26_ SATGA 31_ GPAAA 36_ EKRLG 41_ TPPGG 46_ GGAGA 51_ KEHGN 56_ SVCFK 61_ VDGGG 66_ GGGGG 71_ GGGGE 76_ EPAGG 81_ FEDAE 86_ GPRRQ 91_ YGFMQ 96_ RQFTS 101_ MLQPG 106_ VNKFS 111_ LRMFG 116_ SQKAV 121_ EKEQE 126_ RVKTA 131_ GFWII 136_ HPYSD 141_ FRFYW 146_ DLIML 151_ IMMVG 156_ NLVII 161_ PVGIT 166_ FFTEQ 171_ TTTPW 176_ IIFNV 181_ ASDTV 186_ FLLDL 191_ IMNFR 196_ TGTVN 201_ EDSSE 206_ IILDP 211_ KVIKM 216_ NYLKS 221_ WFVVD 226_ FISSI 231_ PVDYI 236_ FLIVE 241_ KGMDS 246_ EVYKT 251_ ARALR 256_ IVRFT 261_ KILSL 266_ LRLLR 271_ LSRLI 276_ RYIHQ 281_ WEEIF 286_ HMTYD 291_ LASAV 296_ VRIFN 301_ LIGMM 306_ LLLCH 311_ WDGCL 316_ QFLVP 321_ LLQDF 326_ PPDCW 331_ VSLNE 336_ MVNDS 341_ WGKQY 346_ SYALF 351_ KAMSH 356_ MLCIG 361_ YGAQA 366_ PVSMS 371_ DLWIT 376_ MLSMI 381_ VGATC 386_ YAMFV 391_ GHATA 396_ LIQSL 401_ DSSRR 406_ QYQEK 411_ YKQVE 416_ QYMSF 421_ HKLPA 426_ DMRQK 431_ IHDYY 436_ EHRYQ 441_ GKIFD 446_ EENIL 451_ NELND 456_ PLREE 461_ IVNFN 466_ CRKLV 471_ ATMPL 476_ FANAD 481_ PNFVT 486_ AMLSK 491_ LRFEV 496_ FQPGD 501_ YIIRE 506_ GAVGK 511_ KMYFI 516_ QHGVA 521_ GVITK 526_ SSKEM 531_ KLTDG 536_ SYFGE 541_ ICLLT 546_ KGRRT 551_ ASVRA 556_ DTYCR 561_ LYSLS 566_ VDNFN 571_ EVLEE 576_ YPMMR 581_ RAFET 586_ VAIDR 591_ LDRIG 596_ KKNSI 601_ LLQKF 606_ QKDLN 611_ TGVFN 616_ NQENE 621_ ILKQI 626_ VKHDR 631_ EMVQA 636_ IAPIN 641_ YPQMT 646_ TLNST 651_ SSTTT 656_ PTSRM 661_ RTQSP 666_ PVYTA 671_ TSLSH 676_ SNLHS 681_ PSPST 686_ QTPQP 691_ SAILS 696_ PCSYT 701_ TAVCS 706_ PPVQS 711_ PLAAR 716_ TFHYA 721_ SPTAS 726_ QLSLM 731_ QQQPQ 736_ QQVQQ 741_ SQPPQ 746_ TQPQQ 751_ PSPQP 756_ QTPGS 761_ STPKN 766_ EVHKS 771_ TQALH 776_ NTNLT 781_ REVRP 786_ LSASQ 791_ PSLPH 796_ EVSTL 801_ ISRPH 806_ PTVGE 811_ SLASI 816_ PQPVT 821_ AVPGT 826_ GLQAG 831_ GRSTV 836_ PQRVT 841_ LFRQM 846_ SSGAI 851_ PPNRG 856_ VPPAP 861_ PPPAA 866_ ALPRE 871_ SSSVL 876_ NTDPD 881_AEKPR
1: Hyperpolarization-activated ion channel that are permeable to sodium and potassium ions (PubMed:15351778, PubMed:28086084). Displays lower selectivity for K(+) over Na(+) ions (PubMed:28086084). Contributes to the native pacemaker currents in heart (If) and in the generation of the I(h) current which controls neuron excitability (PubMed:29936235, PubMed:30351409). Participates in cerebellar mechanisms of motor learning (By similarity). May mediate responses to sour stimuli (By similarity)