Dolichol-phosphate mannosyltransferase subunit 1 (EC 2.4.1.83) (Dolichol-phosphate mannose synthase subunit 1) (DPM synthase subunit 1) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 1) (Mannose-P-dolichol synthase subunit 1) (MPD synthase subunit 1)
1_MASLE 6_ VSRSP 11_ RRSRR 16_ ELEVR 21_ SPRQN 26_ KYSVL 31_ LPTYN 36_ ERENL 41_ PLIVW 46_ LLVKS 51_ FSESG 56_ INYEI 61_ IIIDD 66_ GSPDG 71_ TRDVA 76_ EQLEK 81_ IYGSD 86_ RILLR 91_ PREKK 96_ LGLGT 101_ AYIHG 106_ MKHAT 111_ GNYII 116_ IMDAD 121_ LSHHP 126_ KFIPE 131_ FIRKQ 136_ KEGNF 141_ DIVSG 146_ TRYKG 151_ NGGVY 156_ GWDLK 161_ RKIIS 166_ RGANF 171_ LTQIL 176_ LRPGA 181_ SDLTG 186_ SFRLY 191_ RKEVL 196_ EKLIE 201_ KCVSK 206_ GYVFQ 211_ MEMIV 216_ RARQL 221_ NYTIG 226_ EVPIS 231_ FVDRV 236_ YGESK 241_ LGGNE 246_ IVSFL 251_KGLLT
1: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex