DNA/RNA-binding protein KIN17 (Binding to curved DNA) (KIN, antigenic determinant of recA protein homolog)
1_MGKSD 6_ FLTPK 11_ AIANR 16_ IKSKG 21_ LQKLR 26_ WYCQM 31_ CQKQC 36_ RDENG 41_ FKCHC 46_ MSESH 51_ QRQLL 56_ LASEN 61_ PQQFM 66_ DYFSE 71_ EFRND 76_ FLELL 81_ RRRFG 86_ TKRVH 91_ NNIVY 96_ NEYIS 101_ HREHI 106_ HMNAT 111_ QWETL 116_ TDFTK 121_ WLGRE 126_ GLCKV 131_ DETPK 136_ GWYIQ 141_ YIDRD 146_ PETIR 151_ RQLEL 156_ EKKKK 161_ QDLDD 166_ EEKTA 171_ KFIEE 176_ QVRRG 181_ LEGKE 186_ QEVPT 191_ FTELS 196_ RENDE 201_ EKVTF 206_ NLSKG 211_ ACSSS 216_ GATSS 221_ KSSTL 226_ GPSAL 231_ KTIGS 236_ SASVK 241_ RKESS 246_ QSSTQ 251_ SKEKK 256_ KKKSA 261_ LDEIM 266_ EIEEE 271_ KKRTA 276_ RTDYW 281_ LQPEI 286_ IVKII 291_ TKKLG 296_ EKYHK 301_ KKAIV 306_ KEVID 311_ KYTAV 316_ VKMID 321_ SGDKL 326_ KLDQT 331_ HLETV 336_ IPAPG 341_ KRILV 346_ LNGGY 351_ RGNEG 356_ TLESI 361_ NEKTF 366_ SATIV 371_ IETGP 376_ LKGRR 381_ VEGIQ 386_YEDIS
1: Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo (By similarity). Binds via its C-terminal domain to RNA in vitro