Matrix metalloproteinase-20 (MMP-20) (EC 3.4.24.-) (Enamel metalloproteinase) (Enamelysin)
1_MKVLP 6_ ASGLA 11_ VFLIM 16_ ALKFS 21_ TAAPS 26_ LVAAS 31_ PRTWR 36_ NNYRL 41_ AQAYL 46_ DKYYT 51_ NKEGH 56_ QIGEM 61_ VARGS 66_ NSMIR 71_ KIKEL 76_ QAFFG 81_ LQVTG 86_ KLDQT 91_ TMNVI 96_ KKPRC 101_ GVPDV 106_ ANYRL 111_ FPGEP 116_ KWKKN 121_ TLTYR 126_ ISKYT 131_ PSMSS 136_ VEVDK 141_ AVEMA 146_ LQAWS 151_ SAVPL 156_ SFVRI 161_ NSGEA 166_ DIMIS 171_ FENGD 176_ HGDSY 181_ PFDGP 186_ RGTLA 191_ HAFAP 196_ GEGLG 201_ GDTHF 206_ DNAEK 211_ WTMGT 216_ NGFNL 221_ FTVAA 226_ HEFGH 231_ ALGLA 236_ HSTDP 241_ SALMY 246_ PTYKY 251_ KNPYG 256_ FHLPK 261_ DDVKG 266_ IQALY 271_ GPRKV 276_ FLGKP 281_ TLPHA 286_ PHHKP 291_ SIPDL 296_ CDSSS 301_ SFDAV 306_ TMLGK 311_ ELLLF 316_ KDRIF 321_ WRRQV 326_ HLRTG 331_ IRPST 336_ ITSSF 341_ PQLMS 346_ NVDAA 351_ YEVAE 356_ RGTAY 361_ FFKGP 366_ HYWIT 371_ RGFQM 376_ QGPPR 381_ TIYDF 386_ GFPRH 391_ VQQID 396_ AAVYL 401_ REPQK 406_ TLFFV 411_ GDEYY 416_ SYDER 421_ KRKME 426_ KDYPK 431_ NTEEE 436_ FSGVN 441_ GQIDA 446_ AVELN 451_ GYIYF 456_ FSGPK 461_ TYKYD 466_ TEKED 471_ VVSVV 476_KSSSW
1: Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-|-Phe-361' site