Gene name: FCGR3B

Uniprot entry:

O75015

Protein names:

Low affinity immunoglobulin gamma Fc region receptor III-B (Fc-gamma RIII-beta) (CD16-I) (Fc-gamma RIII) (Fc-gamma RIIIb) (FcRIII) (FcRIIIb) (FcR-10) (IgG Fc receptor III-1) (CD antigen CD16b)

Protein sequence:

1_MWQLL 6_ LPTAL 11_ LLLVS 16_ AGMRT 21_ EDLPK 26_ AVVFL 31_ EPQWY 36_ SVLEK 41_ DSVTL 46_ KCQGA 51_ YSPED 56_ NSTQW 61_ FHNES 66_ LISSQ 71_ ASSYF 76_ IDAAT 81_ VNDSG 86_ EYRCQ 91_ TNLST 96_ LSDPV 101_ QLEVH 106_ IGWLL 111_ LQAPR 116_ WVFKE 121_ EDPIH 126_ LRCHS 131_ WKNTA 136_ LHKVT 141_ YLQNG 146_ KDRKY 151_ FHHNS 156_ DFHIP 161_ KATLK 166_ DSGSY 171_ FCRGL 176_ VGSKN 181_ VSSET 186_ VNITI 191_ TQGLA 196_ VSTIS 201_ SFSPP 206_ GYQVS 211_ FCLVM 216_ VLLFA 221_ VDTGL 226_YFSVK

Protein annotations

Protein functions:

1: Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils