Heat shock factor 2-binding protein
1_MGEAG 6_ AAEEA 11_ CRHMG 16_ TKEEF 21_ VKVRK 26_ KDLER 31_ LTTEV 36_ MQIRD 41_ FLPRI 46_ LNGEV 51_ LESFQ 56_ KLKIV 61_ EKNLE 66_ RKEQE 71_ LEQLK 76_ MDCEH 81_ FKARL 86_ ETVQA 91_ DNIRE 96_ KKEKL 101_ ALRQQ 106_ LNEAK 111_ QQLLQ 116_ QAEYC 121_ TEMGA 126_ AACTL 131_ LWGVS 136_ SSEEV 141_ VKAIL 146_ GGDKA 151_ LKFFS 156_ ITGQT 161_ MESFV 166_ KSLDG 171_ DVQEL 176_ DSDES 181_ QFVFA 186_ LAGIV 191_ TNVAA 196_ IACGR 201_ EFLVN 206_ SSRVL 211_ LDTIL 216_ QLLGD 221_ LKPGQ 226_ CTKLK 231_ VLMLM 236_ SLYNV 241_ SINLK 246_ GLKYI 251_ SESPG 256_ FIPLL 261_ WWLLS 266_ DPDAE 271_ VCLHV 276_ LRLVQ 281_ SVVLE 286_ PEVFS 291_ KSASE 296_ FRSSL 301_ PLQRI 306_ LAMSK 311_ SRNPR 316_ LQTAA 321_ QELLE 326_DLRTL
1: Meiotic recombination factor component of recombination bridges involved in meiotic double-strand break repair. Modulates the localization of recombinases DMC1:RAD51 to meiotic double-strand break (DSB) sites through the interaction with BRCA2 and its recruitment during meiotic recombination (By similarity) (PubMed:31242413). Indispensable for the DSB repair, homologous synapsis, and crossover formation that are needed for progression past metaphase I, is essential for spermatogenesis and male fertility (By similarity). Required for proper recombinase recruitment in female meiosis (By similarity). Inhibits BNC1 transcriptional activity during spermatogenesis, probably by sequestering it in the cytoplasm (By similarity). May be involved in modulating HSF2 activation in testis (PubMed:9651507)