1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-2) (Phosphoinositide phospholipase C-like 4) (PLC-L4) (Phospholipase C-like protein 4) (Phospholipase C-eta-2) (PLC-eta2)
1_MSGPW 6_ PSPDS 11_ RTKGT 16_ VAWLA 21_ EVLLW 26_ VGGSV 31_ VLSSE 36_ WQLGP 41_ LVERC 46_ MGAMQ 51_ EGMQM 56_ VKLRG 61_ GSKGL 66_ VRFYY 71_ LDEHR 76_ SCIRW 81_ RPSRK 86_ NEKAK 91_ ISIDS 96_ IQEVS 101_ EGRQS 106_ EVFQR 111_ YPDGS 116_ FDPNC 121_ CFSIY 126_ HGSHR 131_ ESLDL 136_ VSTSS 141_ EVART 146_ WVTGL 151_ RYLMA 156_ GISDE 161_ DSLAR 166_ RQRTR 171_ DQWLK 176_ QTFDE 181_ ADKNG 186_ DGSLS 191_ IGEVL 196_ QLLHK 201_ LNVNL 206_ PRQRV 211_ KQMFR 216_ EADTD 221_ DHQGT 226_ LGFEE 231_ FCAFY 236_ KMMST 241_ RRDLY 246_ LLMLT 251_ YSNHK 256_ DHLDA 261_ ASLQR 266_ FLQVE 271_ QKMAG 276_ VTLES 281_ CQDII 286_ EQFEP 291_ CPENK 296_ SKGLL 301_ GIDGF 306_ TNYTR 311_ SPAGD 316_ IFNPE 321_ HHHVH 326_ QDMTQ 331_ PLSHY 336_ FITSS 341_ HNTYL 346_ VGDQL 351_ MSQSR 356_ VDMYA 361_ WVLQA 366_ GCRCV 371_ EVDCW 376_ DGPDG 381_ EPIVH 386_ HGYTL 391_ TSKIL 396_ FKDVI 401_ ETINK 406_ YAFIK 411_ NEYPV 416_ ILSIE 421_ NHCSV 426_ IQQKK 431_ MAQYL 436_ TDILG 441_ DKLDL 446_ SSVSS 451_ EDATT 456_ LPSPQ 461_ MLKGK 466_ ILVKG 471_ KKLPA 476_ NISED 481_ AEEGE 486_ VSDED 491_ SADEI 496_ DDDCK 501_ LLNGD 506_ ASTNR 511_ KRVEN 516_ TAKRK 521_ LDSLI 526_ KESKI 531_ RDCED 536_ PNNFS 541_ VSTLS 546_ PSGKL 551_ GRKSK 556_ AEEDV 561_ ESGED 566_ AGASR 571_ RNGRL 576_ VVGSF 581_ SRRKK 586_ KGSKL 591_ KKAAS 596_ VEEGD 601_ EGQDS 606_ PGGQS 611_ RGATR 616_ QKKTM 621_ KLSRA 626_ LSDLV 631_ KYTKS 636_ VATHD 641_ IEMEA 646_ ASSWQ 651_ VSSFS 656_ ETKAH 661_ QILQQ 666_ KPAQY 671_ LRFNQ 676_ QQLSR 681_ IYPSS 686_ YRVDS 691_ SNYNP 696_ QPFWN 701_ AGCQM 706_ VALNY 711_ QSEGR 716_ MLQLN 721_ RAKFS 726_ ANGGC 731_ GYVLK 736_ PGCMC 741_ QGVFN 746_ PNSED 751_ PLPGQ 756_ LKKQL 761_ VLRII 766_ SGQQL 771_ PKPRD 776_ SMLGD 781_ RGEII 786_ DPFVE 791_ VEIIG 796_ LPVDC 801_ SREQT 806_ RVVDD 811_ NGFNP 816_ TWEET 821_ LVFMV 826_ HMPEI 831_ ALVRF 836_ LVWDH 841_ DPIGR 846_ DFIGQ 851_ RTLAF 856_ SSMMP 861_ GYRHV 866_ YLEGM 871_ EEASI 876_ FVHVA 881_ VSDIS 886_ GKVKQ 891_ ALGLK 896_ GLFLR 901_ GPKPG 906_ SLDSH 911_ AAGRP 916_ PARPS 921_ VSQRI 926_ LRRTA 931_ SAPTK 936_ SQKPG 941_ RRGFP 946_ ELVLG 951_ TRDTG 956_ SKGVA 961_ DDVVP 966_ PGPGP 971_ APEAP 976_ AQEGP 981_ GSGSP 986_ RDTRP 991_ LSTQR 996_ PLPPL 1001_ CSLET 1006_ IAEEP 1011_ APGPG 1016_ PPPPA 1021_ AVPTS 1026_ SSQGR 1031_ PPYPT 1036_ GPGAN 1041_ VASPL 1046_ EDTEE 1051_ PRDSR 1056_ PRPCN 1061_ GEGAG 1066_ GAYER 1071_ APGSQ 1076_ TDGRS 1081_ QPRTL 1086_ GHLPV 1091_ IRRVK 1096_ SEGQV 1101_ PTEPL 1106_ GGWRP 1111_ LAAPF 1116_ PAPAV 1121_ YSDAT 1126_ GSDPL 1131_ WQRLE 1136_ PCGHR 1141_ DSVSS 1146_ SSSMS 1151_ SSDTV 1156_ IDLSL 1161_ PSLGL 1166_ GRSRE 1171_ NLAGA 1176_ HMGRL 1181_ PPRPH 1186_ SASAA 1191_ RPDLP 1196_ PVTKS 1201_ KSNPN 1206_ LRATG 1211_ QRPPI 1216_ PDELQ 1221_ PRSLA 1226_ PRMAG 1231_ LPFRP 1236_ PWGCL 1241_ SLVGV 1246_ QDCPV 1251_ AAKSK 1256_ SLGDL 1261_ TADDF 1266_ APSFE 1271_ GGSRR 1276_ LSHSL 1281_ GLPGG 1286_ TRRVS 1291_ GPGVR 1296_ RDTLT 1301_ EQLRW 1306_ LTVFQ 1311_ QAGDI 1316_ TSPTS 1321_ LGPAG 1326_ EGVAG 1331_ GPGFV 1336_ RRSSS 1341_ RSHSR 1346_ VRAIA 1351_ SRARQ 1356_ AQERQ 1361_ QRLQG 1366_ LGRQG 1371_ PPEEE 1376_ RGTPE 1381_ GACSV 1386_ GHEGS 1391_ VDAPA 1396_ PSKGA 1401_ LGPAS 1406_ AAAEN 1411_LVLLR
1: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (PubMed:18361507). This phospholipase activity is very sensitive to calcium. May be important for formation and maintenance of the neuronal network in the postnatal brain (By similarity)